User profiles for Hang Gyeong Chin

Hang Gyeong Chin

New England Biolabs, Inc
Verified email at neb.com
Cited by 4283

Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication

PO Estève, HG Chin, A Smallwood… - Genes & …, 2006 - genesdev.cshlp.org
Chromatin methylation is necessary for stable repression of gene expression during mammalian
development. During cell division, DNMT1 maintains the DNA methylation pattern of the …

[HTML][HTML] Dual binding of chromomethylase domains to H3K9me2-containing nucleosomes directs DNA methylation in plants

…, S Feng, E Caro, AA Vashisht, J Terragni, HG Chin… - Cell, 2012 - cell.com
DNA methylation and histone modification exert epigenetic control over gene expression. CHG
methylation by CHROMOMETHYLASE3 (CMT3) depends on histone H3K9 dimethylation …

Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells

PO Estève, HG Chin, J Benner… - Proceedings of the …, 2009 - National Acad Sciences
Inheritance of epigenetic information encoded by cytosine DNA methylation patterns is
crucial for mammalian cell survival, in large part through the activity of the maintenance DNA …

[PDF][PDF] Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation

N Ding, H Zhou, PO Esteve, HG Chin, S Kim, X Xu… - Molecular cell, 2008 - cell.com
Mediator occupies a central role in RNA polymerase II transcription as a sensor, integrator,
and processor of regulatory signals that converge on protein-coding gene promoters. …

[HTML][HTML] Tissue-specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genomes

SM Kinney, HG Chin, R Vaisvila, J Bitinaite… - Journal of Biological …, 2011 - ASBMB
Cytosine residues in the vertebrate genome are enzymatically modified to 5-methylcytosine,
which participates in transcriptional repression of genes during development and disease …

Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters

PO Estève, HG Chin, S Pradhan - Proceedings of the …, 2005 - National Acad Sciences
DNA (cytosine-5)-methyltransferase (DNMT) 1 participates in transcriptional repression of
genes by methylation-dependent and -independent mechanisms. Here, DNMT1 is shown to …

[HTML][HTML] Substrate specificity and kinetic mechanism of mammalian G9a histone H3 methyltransferase

D Patnaik, HG Chin, PO Esteve, J Benner… - Journal of Biological …, 2004 - ASBMB
Lysine-specific murine histone H3 methyltransferase, G9a, was expressed and purified in a
baculovirus expression system. The primary structure of the recombinant enzyme is identical …

Molecular analysis of rice plants harboring an Ac/Ds transposable element‐mediated gene trapping system

HG Chin, MS Choe, SH Lee, SH Park… - The Plant …, 1999 - Wiley Online Library
In rice, limited efforts have been made to identify genes by the use of insertional mutagens,
especially hetero‐ logous transposons such as the maize Ac/Ds. We constructed Ac and …

SET7/9 mediated methylation of non-histone proteins in mammalian cells

S Pradhan, HG Chin, PO Estève, SE Jacobsen - Epigenetics, 2009 - Taylor & Francis
Lysine methylation has emerged as a major posttranslational modification for histones in
eukaryotes. Crosstalk between lysine methylation and other posttranslational modifications is …

Automethylation of G9a and its implication in wider substrate specificity and HP1 binding

HG Chin, PO Esteve, M Pradhan, J Benner… - Nucleic acids …, 2007 - academic.oup.com
Methylation of lysine residues on histones participates in transcriptional gene regulation.
Lysine 9 methylation of histone H3 is a transcriptional repression signal, mediated by a family …