Population isolates such as those in Finland benefit genetic research because deleterious
alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor …

Population isolates such as Finland provide benefits in genetic studies because the allelic
spectrum of damaging alleles in any gene is often concentrated on a small number of low-…

Importance The causal direction and magnitude of the association between telomere length
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …

Clinical laboratory tests are a critical component of the continuum of care. We evaluate the
genetic basis of 35 blood and urine laboratory measurements in the UK Biobank (n = 363,228 …

In developed countries, the majority of all violent crime is committed by a small group of
antisocial recidivistic offenders, but no genes have been shown to contribute to recidivistic …

Narcolepsy is a chronic sleep disorder that has a typical onset in adolescence and is
characterized by excessive daytime sleepiness, which can have severe consequences for the …

Vascular endothelial growth factor (VEGF)-B is poorly angiogenic but prominently expressed
in metabolically highly active tissues, including the heart. We produced mice expressing a …

Background Obstructive sleep apnoea (OSA) is associated with higher body mass index (BMI),
diabetes, older age and male gender, which are all risk factors for severe COVID-19. We …

Daytime napping is a common, heritable behavior, but its genetic basis and causal
relationship with cardiometabolic health remain unclear. Here, we perform a genome-wide …

We used crowdsourcing (CS) to examine how COVID-19 lockdown affects the content of
dreams and nightmares. The CS took place on the sixth week of the lockdown. Over the course …