[HTML][HTML] Inhibition of Bruton's tyrosine kinase activity attenuates hemorrhagic shock-induced multiple organ dysfunction in rats

NM Patel, FRMB Oliveira, HP Ramos… - Annals of …, 2023 - journals.lww.com
Objective: The aim of this study was to investigate (a) the potential of the Bruton's tyrosine
kinase (BTK) inhibitors acalabrutinib and fenebrutinib to reduce multiple organ dysfunction …

[HTML][HTML] Inhibition of macrophage migration inhibitory factor activity attenuates haemorrhagic shock-induced multiple organ dysfunction in rats

…, M Collino, D Collotta, GF Alves, HP Ramos… - Frontiers in …, 2022 - frontiersin.org
Objective The aim of this study was to investigate (a) macrophage migration inhibitory factor
(MIF) levels in polytrauma patients and rats after haemorrhagic shock (HS), (b) the potential …

Vitamin C decreases reduced glutathione in chronic haemodialysis patients: a pilot, randomised, double-blind trial

…, AT da Silva, RP Machado, HP Ramos… - … Urology and Nephrology, 2021 - Springer
Purpose Whey protein has antioxidant properties through its amino acid cysteine, which
enhances the biosynthesis of glutathione, the most abundant antioxidant non-protein in …

The inhibition of macrophage migration inhibitory factor by ISO-1 attenuates trauma-induced multi organ dysfunction in rats

…, C Stoppe, M Collino, D Collotta, GF Alves, HP Ramos… - medRxiv, 2021 - medrxiv.org
Background Multi organ dysfunction syndrome caused by systemic inflammation after trauma
is responsible for a high number of deaths worldwide. The cytokine Migration Inhibitory …

Ilex paraguariensis (A. St.-Hil.) leaf infusion decreases iron absorption in patients with hereditary hemochromatosis: a randomized controlled crossover study

…, FGK Vieira, BV Dias, VKB Franco, HP Ramos… - Food & Function, 2021 - pubs.rsc.org
This study proposed to investigate the effect of Ilex paraguariensis infusion on the absorption
of non-heme iron in hereditary hemochromatosis (HH) patients with the HFE genotype. A …

Inhibition of Bruton's tyrosine kinase activity attenuates trauma-induced multiple organ dysfunction in rats

NM Patel, FRMB Oliveira, HP Ramos, E Aimaretti… - bioRxiv, 2021 - biorxiv.org
Objective The aim of this study was to investigate (a) the potential of the Bruton’s tyrosine
kinase (BTK) inhibitors (BTKi) acalabrutinib and fenebrutinib to reduce multiple organ …

New Therapeutic Approaches for Haemorrhagic Shock

N Patel - 2022 - qmro.qmul.ac.uk
Trauma is one of the leading causes of death and disability, affecting 6 million people
annually worldwide. Haemorrhagic shock (HS), which causes hypoperfusion of organs and …

[HTML][HTML] Three-Dimensional Genome Organization in breast and gynecological cancers: how chromatin folding influences Tumorigenic Transcriptional Programs

SI Nuñez-Olvera, J Puente-Rivera, R Ramos-Payán… - Cells, 2021 - mdpi.com
A growing body of research on the transcriptome and cancer genome has demonstrated that
many gynecological tumor-specific gene mutations are located in cis-regulatory elements. …

Excavations at Las Huacas (AD 1200-1650): Exploring Elite Strategies and Economic Exchange During the Inca Empire

J Dalton - 2020 - deepblue.lib.umich.edu
The complex and dynamic strategies of ancient states and empires have been documented
throughout the world. The Inca Empire of Peru created a massive empire that extended from …

[PDF][PDF] Evolution of adaptations to temperate climate in the grass subfamily Pooideae

M Schubert - 2016 - nmbu.brage.unit.no
Temperate biomes are characterized by strong temperature and photoperiod seasonality
and frequently occurring frost. Temperate plants have evolved to overcome challenges like …