ECHO: an application for detection and analysis of oscillators identifies metabolic regulation on genome-wide circadian output
H De los Santos, EJ Collins, C Mann, AW Sagan… - …, 2020 - academic.oup.com
Motivation Time courses utilizing genome scale data are a common approach to identifying
the biological pathways that are controlled by the circadian clock, an important regulator of …
the biological pathways that are controlled by the circadian clock, an important regulator of …
[PDF][PDF] Circadian proteomic analysis uncovers mechanisms of post-transcriptional regulation in metabolic pathways
JM Hurley, MS Jankowski, H De los Santos… - Cell systems, 2018 - cell.com
Transcriptional and translational feedback loops in fungi and animals drive circadian rhythms
in transcript levels that provide output from the clock, but post-transcriptional mechanisms …
in transcript levels that provide output from the clock, but post-transcriptional mechanisms …
Encore: a visualization tool for insight into circadian omics
H De los Santos, KP Bennett, JM Hurley - Proceedings of the 10th ACM …, 2019 - dl.acm.org
Circadian rhythms are 24-hour biological cycles that control daily molecular rhythms in many
organisms. The cellular elements that fall under the regulation of the clock are often studied …
organisms. The cellular elements that fall under the regulation of the clock are often studied …
Reaction of O6-alkylguanine-DNA alkyltransferase with O6-methylguanine analogs: evidence that the oxygen of O6-methylguanine is protonated by the protein to …
TE Spratt, H De los Santos - Biochemistry, 1992 - ACS Publications
Revised Manuscript Received February 3, 1992 abstract: The DNA repair protein ú^-alkylguanine-DNA
alkyltransferase (AGT) repairs the promutagenic O^ methylguanine lesion by …
alkyltransferase (AGT) repairs the promutagenic O^ methylguanine lesion by …
The effect of Gymnema sylvestre extracts on the sweetness of eight sweeteners
…, SJS Mize, LM Kennedy, HC de los Santos… - Chemical …, 1992 - academic.oup.com
Although numerous experiments have demonstrated the sweetness-inhibiting effects of
Gymnema sylvestre extracts, no human psychophysical studies have been done to quantitatively …
Gymnema sylvestre extracts, no human psychophysical studies have been done to quantitatively …
MOSAIC: a joint modeling methodology for combined circadian and non-circadian analysis of multi-omics data
H De los Santos, KP Bennett, JM Hurley - Bioinformatics, 2021 - academic.oup.com
Motivation Circadian rhythms are approximately 24-h endogenous cycles that control many
biological functions. To identify these rhythms, biological samples are taken over circadian …
biological functions. To identify these rhythms, biological samples are taken over circadian …
[HTML][HTML] Identifying windows of susceptibility by temporal gene analysis
KP Bennett, EM Brown, HD Santos, M Poegel… - Scientific Reports, 2019 - nature.com
Increased understanding of developmental disorders of the brain has shown that genetic
mutations, environmental toxins and biological insults typically act during developmental …
mutations, environmental toxins and biological insults typically act during developmental …
Circadian Rhythms in Neurospora Exhibit Biologically Relevant Driven and Damped Harmonic Oscillations
H De los Santos, EJ Collins, JM Hurley… - Proceedings of the 8th …, 2017 - dl.acm.org
Circadian rhythms are endogenous cycles of approximately 24 hours reinforced by external
cues such as light. These cycles are typically modeled as harmonic oscillators with fixed …
cues such as light. These cycles are typically modeled as harmonic oscillators with fixed …
Evaluating Methods for Mapping Historical Redlining to Census Tracts for Health Equity Research
H De los Santos, CP Bezold, KM Jiang, JT Chen… - Journal of Urban …, 2024 - Springer
Neighborhood characteristics including housing status can profoundly influence health.
Recently, increasing attention has been paid to present-day impacts of “redlining,” or historic …
Recently, increasing attention has been paid to present-day impacts of “redlining,” or historic …
The PAICE suite reveals circadian posttranscriptional timing of noncoding RNAs and spliceosome components in Mus musculus macrophages
SM Buel, S Debopadhaya, H De los Santos… - G3, 2022 - academic.oup.com
Circadian rhythms broadly regulate physiological functions by tuning oscillations in the levels
of mRNAs and proteins to the 24-h day/night cycle. Globally assessing which mRNAs and …
of mRNAs and proteins to the 24-h day/night cycle. Globally assessing which mRNAs and …