Synapse density is reduced in postmortem cortical tissue from schizophrenia patients, which
is suggestive of increased synapse elimination. Using a reprogrammed in vitro model of …

This article reviews the current literature addressing the treatment of schizophrenia with vitamin
supplementation. It describes the important roles that vitamins play in normal metabolism…

Background Relying on diagnostic categories of neuropsychiatric illness obscures the complexity
of these disorders. Capturing multiple dimensional measures of neuropathology could …

BACKGROUND. Patients with schizophrenia (SCZ) experience chronic cognitive deficits.
Histone deacetylases (HDACs) are enzymes that regulate cognitive circuitry; however, the role …

Folic acid supplementation confers modest benefit in schizophrenia, but its effectiveness is
influenced by common genetic variants in the folate pathway that hinder conversion to its …

Chitin and chitosan are two related polysaccharides that provide important structural stability
to fungal cell walls. Often embedded deeply within the cell wall structure, these molecules …

The cytokine gamma interferon (IFN-γ) induces cell-autonomous immunity to combat infections
with intracellular pathogens, such as the bacterium Chlamydia trachomatis . The present …

A measure of planning and impulse control, the delay-discounting (DD) task estimates the
extent to which an individual decreases the perceived value of a reward as the reward is …

The etiology of bipolar disorder (BD) is unknown and the neurobiological underpinnings are
not fully understood. Both genetic and environmental factors contribute to the risk of BD, …

The ability for cells to maintain homeostasis in the presence of extracellular stress is essential
for their survival. Stress adaptations are especially important for microbial pathogens to …