Sex differences in the role of CNIH3 on spatial memory and synaptic plasticity

HE Frye, Y Izumi, AN Harris, SB Williams… - Biological …, 2021 - Elsevier
Background CNIH3 is an AMPA receptor (AMPAR) auxiliary protein prominently expressed
in the dorsal hippocampus (dHPC), a region that plays a critical role in spatial memory and …

Cnih3 Deletion Dysregulates Dorsal Hippocampal Transcription across the Estrous Cycle

B Mulvey, HE Frye, T Lintz, S Fass, E Tycksen… - Eneuro, 2023 - eneuro.org
In females, the hippocampus, a critical brain region for coordination of learning, memory,
and behavior, displays altered physiology and behavioral output across the estrous or …

Typical hippocampal transcriptional response across estrous is dysregulated by Cnih3 gene deletion

B Mulvey, HE Frye, T Lintz, S Fass, E Tycksen… - bioRxiv, 2022 - biorxiv.org
The hippocampus is a critical brain region for coordinating learning, memory, and behavior.
In females, the estrous cycle alters these functions through steroid hormone activity, with well…

[HTML][HTML] Policy Memo: Genetic Privacy Consumer Protections

HE Frye, E Kotnik, R Rahn - sites.wustl.edu
Direct-to-consumer genetic testing companies have become increasingly popular in the US
as DNA sequencing technology has become more advanced and less expensive. But this …

Cornichon Homolog-3 (CNIH3) Modulates Spatial Memory in Female Mice

HE Frye, SB Williams, CR Trousdale, EC Nelson… - bioRxiv, 2019 - biorxiv.org
Cornichon homolog-3 (CNIH3) is an AMPA receptor (AMPAR) auxiliary protein that traffics
AMPARs to the postsynaptic membrane and potentiates AMPAR signaling. AMPARs are key …

[HTML][HTML] Policy Memo: Motor Vehicle Crash Testing Regulations for More Inclusive Populations

HE Frye, D Ko, E Kotnik, N Zelt - sites.wustl.edu
There is a stark disparity in motor vehicle crash deaths and injuries between male and female
drivers. Female drivers are 13% more likely to be killed than their male counterparts in …

[PDF][PDF] Motor vehicle crash testing regulations for more inclusive populations

H Frye, D Ko, E Kotnik, N Zelt - J Sci Policy Gov, 2021 - sciencepolicyjournal.org
Hannah E. Frye, Ph.D. received her doctoral degree in Neuroscience from Washington …
Frye served as the Policy and Advocacy Chair in 2019 – 2020 for Promoting Science Policy, …

Metabolic pathology of autism in relation to redox metabolism

RE Frye, SJ James - Biomarkers in medicine, 2014 - Future Medicine
… Richard E Frye … Richard E Frye … Recently Frye et al. [37] demonstrated a very high
prevalence of the blocking (60%) and binding (44%) FRαs in ASD children in an uncontrolled study. …

MERTK mediates intrinsic and adaptive resistance to AXL-targeting agents

…, GH Kang, KD Davies, X Wang, SV Frye… - Molecular cancer …, 2018 - AACR
The TAM (TYRO3, AXL, MERTK) family receptor tyrosine kinases (RTK) play an important
role in promoting growth, survival, and metastatic spread of several tumor types. AXL and …

Aryl–Aryl Bond Formation by the Fluoride‐Free Cross‐Coupling of Aryldisiloxanes with Aryl Bromides

CM Boehner, EC Frye, KMG O'Connell… - … A European Journal, 2011 - Wiley Online Library
The prevalence of the biaryl structural motif in biologically interesting and synthetically
important molecules has inspired considerable interest in the development of methods for aryl–…