Natural products play critical roles as antibiotics, anticancer therapeutics, and biofuels.
Polyketides are a distinct natural product class of structurally diverse secondary metabolites that …

Natural product discovery has traditionally relied on the isolation of small molecules from
producing species, but genome‐sequencing technology and advances in molecular biology …

Type I polyketide synthases (PKSs) are multidomain, multimodule enzymes capable of
producing complex polyketide metabolites. These modules contain an acyltransferase (AT) …

Adenylate-forming enzymes represent one of the most important enzyme classes in biology,
responsible for the activation of carboxylate substrates for biosynthetic modifications. The …

Polyketide synthases (PKSs) are megaenzymes that form chemically diverse polyketides and
are found within the genomes of nearly all classes of life. We recently discovered the type I …

Anopheles mosquito microbiomes are intriguing ecological niches. Within the gut, microbes
adapt to oxidative stress due to heme and iron after blood meals. Although metagenomic …

A mathematical model for the effect of the spatial variation of the local evaporative flux on
the evaporation of and deposition from a thin pinned particle-laden sessile droplet is …

Trehalose is a disaccharide produced by many organisms to better enable them to survive
environmental stresses, including heat, cold, desiccation, and reactive oxygen species. …

This thesis concerns the theoretical modelling and analysis of the evolution of, and the
deposition from, an evaporating sessile droplet. In particular, the thesis focuses on the diffusion-…

Fluoreno[2,1-a]fluorene, a molecule comprising fused ortho-quinodimethane units in a 1,5-napthoquinodimethane
core, has been prepared and investigated with spectroscopy (UV-Vis-…