Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as
BRCA1, and many common, mostly non-coding variants. However, much of the genetic …

Stratification of women according to their risk of breast cancer based on polygenic risk scores
(PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, …

Background: Data for multiple common susceptibility alleles for breast cancer may be combined
to identify women at different levels of breast cancer risk. Such stratification could guide …

Most common breast cancer susceptibility variants have been identified through genome-wide
association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease 1 . …

Breast cancer susceptibility variants frequently show heterogeneity in associations by tumor
subtype 1 , 2 – 3 . To identify novel loci, we performed a genome-wide association study …

This working paper summarises the main findings of a data collection exercise documenting
the size of the national state-owned enterprise (SOE) sectors in OECD countries (in terms of …

Competitive neutrality implies that no business entity is advantaged (or disadvantaged) solely
because of its ownership. The Paper argues that far from all SOEs have the opportunity or …

The breast cancer risk variants identified in genome-wide association studies explain only a
small fraction of the familial relative risk, and the genes responsible for these associations …

Objective To report the oncologic and functional outcomes of transoral laser microsurgery (TLM)
in the treatment of advanced laryngeal cancer. Design Prospective case series study. …

Objective: To assess the feasibility of transoral laser microsurgery (TLM) in the treatment of
hypopharyngeal cancer, with a special focus on piriform sinus carcinomas, and to report the …