A defining property of retroviruses is their ability to assemble into particles that can leave
producer cells and spread infection to susceptible cells and hosts. Virion morphogenesis can …

Viruses intricately interact with and modulate cellular membranes at several stages of their
replication, but much less is known about the role of viral lipids compared to proteins and …

Assembly of human immunodeficiency virus type 1 is driven by oligomerization of the Gag
polyprotein at the plasma membrane of an infected cell, leading to membrane envelopment …

Hepatitis C virus (HCV) infection causes chronic liver diseases and is a global public health
problem. Detailed analyses of HCV have been hampered by the lack of viral culture systems…

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virions are surrounded by
a lipid bilayer from which spike (S) protein trimers protrude 1 . Heavily glycosylated S trimers …

The coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 (severe
acute respiratory syndrome coronavirus 2) coronavirus is a major public health challenge. …

HIV release requires TSG101, a cellular factor that sorts proteins into vesicles that bud into
multivesicular bodies (MVB). To test whether other proteins involved in MVB biogenesis (the …

The lipids of enveloped viruses play critical roles in viral morphogenesis and infectivity. They
are derived from the host membranes from which virus budding occurs, but the precise lipid …

Mature, infectious HIV‐1 particles contain a characteristic cone‐shaped core that encases
the viral RNA and replication proteins. The architectures of mature virions and isolated cores …

The major structural components of HIV-1 are encoded as a single polyprotein, Gag, which
is sufficient for virus particle assembly. Initially, Gag forms an approximately spherical shell …