User profiles for Haojiang Lu
 | Haojiang LuKarolinska Institutet Verified email at ki.se Cited by 590 |
Prenatal androgen exposure and transgenerational susceptibility to polycystic ovary syndrome
How obesity and elevated androgen levels in women with polycystic ovary syndrome (PCOS)
affect their offspring is unclear. In a Swedish nationwide register-based cohort and a …
affect their offspring is unclear. In a Swedish nationwide register-based cohort and a …
[HTML][HTML] Single-cell analysis of human ovarian cortex identifies distinct cell populations but no oogonial stem cells
…, S Panula, S Petropoulos, H Lu… - Nature …, 2020 - nature.com
The human ovary orchestrates sex hormone production and undergoes monthly structural
changes to release mature oocytes. The outer lining of the ovary (cortex) has a key role in …
changes to release mature oocytes. The outer lining of the ovary (cortex) has a key role in …
[HTML][HTML] Origins and impact of psychological traits in polycystic ovary syndrome
Women with polycystic ovary syndrome (PCOS) exhibit compromised psychiatric health.
Independent of obesity, women with PCOS are more susceptible to have anxiety and …
Independent of obesity, women with PCOS are more susceptible to have anxiety and …
[HTML][HTML] Prenatal androgen exposure causes a sexually dimorphic transgenerational increase in offspring susceptibility to anxiety disorders
If and how obesity and elevated androgens in women with polycystic ovary syndrome (PCOS)
affect their offspring’s psychiatric health is unclear. Using data from Swedish population …
affect their offspring’s psychiatric health is unclear. Using data from Swedish population …
[PDF][PDF] Transgenerational transmission of reproductive and metabolic dysfunction in the male progeny of polycystic ovary syndrome
The transgenerational maternal effects of polycystic ovary syndrome (PCOS) in female progeny
are being revealed. As there is evidence that a male equivalent of PCOS may exists, we …
are being revealed. As there is evidence that a male equivalent of PCOS may exists, we …
[HTML][HTML] Transcriptomic survey of key reproductive and metabolic tissues in mouse models of polycystic ovary syndrome
Excessive androgen production and obesity are key to polycystic ovary syndrome (PCOS)
pathogenesis. Prenatal androgenized (PNA), peripubertal androgenized, and overexpression …
pathogenesis. Prenatal androgenized (PNA), peripubertal androgenized, and overexpression …
Proteomic analysis shows decreased type I fibers and ectopic fat accumulation in skeletal muscle from women with PCOS
Background: Polycystic ovary syndrome’s (PCOS) main feature is hyperandrogenism, which
is linked to a higher risk of metabolic disorders. Gene expression analyses in adipose tissue …
is linked to a higher risk of metabolic disorders. Gene expression analyses in adipose tissue …
The role of B cells in immune cell activation in polycystic ovary syndrome
Variations in B cell numbers are associated with polycystic ovary syndrome (PCOS) through
unknown mechanisms. Here, we demonstrate that B cells are not central mediators of PCOS …
unknown mechanisms. Here, we demonstrate that B cells are not central mediators of PCOS …
[HTML][HTML] Extracellular localisation of the C-terminus of DDX4 confirmed by immunocytochemistry and fluorescence-activated cell sorting
…, E Weatherall, M Waterfall, M McLaughlin, H Lu… - Cells, 2019 - mdpi.com
Putative oogonial stem cells (OSCs) have been isolated by fluorescence-activated cell sorting
(FACS) from adult human ovarian tissue using an antibody against DEAD-box helicase 4 (…
(FACS) from adult human ovarian tissue using an antibody against DEAD-box helicase 4 (…
Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice
M Manti, HP Pui, S Edström, S Risal, H Lu… - The FASEB …, 2020 - Wiley Online Library
Nerve growth factor (NGF) is critical for the development and maintenance of the peripheral
sympathetic neurons. NGF is also involved in the ovarian sympathetic innervation and in the …
sympathetic neurons. NGF is also involved in the ovarian sympathetic innervation and in the …