[HTML][HTML] High frequency of cerebrospinal fluid autoantibodies in COVID-19 patients with neurological symptoms

C Franke, C Ferse, J Kreye, SM Reincke… - Brain, behavior, and …, 2021 - Elsevier
Background COVID-19 intensive care patients can present with neurological syndromes,
usually in the absence of SARS-CoV-2 in cerebrospinal fluid (CSF). The recent finding of some …

A clinical approach to diagnosis of autoimmune encephalitis

…, SR Irani, E Lancaster, F Leypoldt, H Prüss… - The lancet …, 2016 - thelancet.com
Encephalitis is a severe inflammatory disorder of the brain with many possible causes and a
complex differential diagnosis. Advances in autoimmune encephalitis research in the past …

N‐methyl‐D‐aspartate receptor antibodies in herpes simplex encephalitis

H Prüss, C Finke, M Höltje, J Hofmann… - Annals of …, 2012 - Wiley Online Library
Objective: To determine the presence and kinetics of antibodies against synaptic proteins in
patients with herpes simplex virus encephalitis (HSE). Methods: Retrospective analysis of …

Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants

…, RW Sanders, DR Burton, SM Reincke, H Prüss… - Science, 2021 - science.org
Neutralizing antibodies (nAbs) elicited against the receptor binding site (RBS) of the spike
protein of wild-type severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are …

Neurofascin as a target for autoantibodies in peripheral neuropathies

…, C Linington, M Odaka, B Tackenberg, H Prüss… - Neurology, 2012 - AAN Enterprises
Objectives: We asked whether autoantibodies against neurofascin (NF)186 or NF155, both
localized at the nodes of Ranvier, are present in serum of patients with inflammatory …

[HTML][HTML] Autoantibodies in neurological disease

H Prüss - Nature reviews immunology, 2021 - nature.com
The realization that autoantibodies can contribute to dysfunction of the brain has brought
about a paradigm shift in neurological diseases over the past decade, offering up important …

[PDF][PDF] A therapeutic non-self-reactive SARS-CoV-2 antibody protects from lung pathology in a COVID-19 hamster model

…, LE Sander, N Osterrieder, IA Wilson, H Prüss - Cell, 2020 - cell.com
The emergence of SARS-CoV-2 led to pandemic spread of coronavirus disease 2019 (COVID-19),
manifesting with respiratory symptoms and multi-organ dysfunction. Detailed …

Updated diagnostic criteria for paraneoplastic neurologic syndromes

…, B Joubert, F Leypoldt, A McKeon, H Prüss… - Neurology …, 2021 - AAN Enterprises
Objective The contemporary diagnosis of paraneoplastic neurologic syndromes (PNSs)
requires an increasing understanding of their clinical, immunologic, and oncologic heterogeneity…

Cognitive deficits following anti-NMDA receptor encephalitis

C Finke, UA Kopp, H Prüss, J Dalmau… - Journal of Neurology …, 2012 - jnnp.bmj.com
Background Anti-NMDA receptor (NMDAR) encephalitis is a recently characterised
autoimmune disorder mainly affecting young women. Although the clinical features of the acute …

Autoimmune psychosis: an international consensus on an approach to the diagnosis and management of psychosis of suspected autoimmune origin

…, BR Lennox, S Müller, ME Benros, H Prüss… - The Lancet …, 2020 - thelancet.com
There is increasing recognition in the neurological and psychiatric literature of patients with
so-called isolated psychotic presentations (ie, with no, or minimal, neurological features) …