Large numbers of sequences are now readily available for many plant species, allowing
easy identification of homologous genes. However, orthologous gene identification across …

The International Cancer Genome Consortium (ICGC)’s Pan-Cancer Analysis of Whole
Genomes (PCAWG) project aimed to categorize somatic and germline variations in both coding …

Results Sex-biases in driver genes, mutation load and tumour evolution. We began by
investigating sex differences in driver gene mutation frequencies, focusing on 165 coding and …

The R2R3-MYB proteins comprise one of the largest families of transcription factors in plants.
R2R3-MYB family members regulate plant-specific processes, such as the elaboration of …

Background The exploration of microarray data and data from other high-throughput projects
for hypothesis generation has become a vital aspect of post-genomic research. For the non-…

The innate immune system is an ancient and broad-spectrum defense system found in all
eukaryotes. The detection of microbial elicitors results in the up-regulation of defense-related …

Adventitious shoot organogenesis contributes to the fitness of diverse plant species, and
control of this process is a vital step in plant transformation and in vitro propagation. New shoot …

Background Imbibed seeds integrate environmental and endogenous signals to break
dormancy and initiate growth under optimal conditions. Seed maturation plays an important role …

Determining the complete Arabidopsis (Arabidopsis thaliana) protein-protein interaction
network is essential for understanding the functional organization of the proteome. Numerous …

Background Identification of protein-protein interactions is a fundamental aspect of understanding
protein function. A commonly used method for identifying protein interactions is the …