The environmental drivers of influenza outbreaks are largely unknown. Despite more than
50 years of research, there are conflicting lines of evidence on the role of the environment in …

Since May 2013, outbreaks of porcine epidemic diarrhea have devastated the US swine
industry, causing immense economic losses. Two different swine enteric coronaviruses (porcine …

Highlights • Emergence of novel animal strains of HEV transmissible to human. • Genotype
1 HEV outbreaks among displaced population with poor sanitation conditions. • Emergence …

As the coronavirus disease 2019 (COVID-19) pandemic rages on, it is important to explore
new evolution-resistant vaccine antigens and new vaccine platforms that can produce readily …

Hepatitis E virus (HEV) infection in pregnant women has a high incidence of developing
fulminant hepatic failure (FHF) with significant mortality. Multiple amino acid changes in …

Swine hepatitis E virus (swine HEV) belongs to the species Orthohepevirus A within the
genus Orthohepevirus in the family Hepeviridae. Four different genotypes of swine HEV within …

Hepatitis E virus (HEV) RNA was detected in 6.3% and HEV IgG in 40% of 5,033 serum
samples from market-weight pigs at 25 slaughterhouses in 10 US states. The prevalent HEV …

Hepatitis E virus (HEV) causes adverse clinical outcomes in pregnant women, but the
underlying mechanisms remain poorly understood. To delineate the mechanisms of pregnancy-…

Hepatitis E virus (HEV), a single-stranded positive-sense RNA virus, generally causes self-limiting
acute viral hepatitis, although chronic HEV infection has recently become a significant …

Progesterone is crucial for the maintenance of pregnancy. During pregnancy hepatitis E virus
(HEV) infection is associated with increased fulminant hepatic failure and mortality rates. In …