Omega-3-fatty acid DHA is a structural component of brain plasma membranes, thereby
crucial for neuronal signaling; however, the brain is inefficient at synthesizing DHA. We have …

Spatial molecular profiling of complex tissues is essential to investigate cellular function in
physiological and pathological states. However, methods for molecular analysis of large …

The bone marrow in the skull is important for shaping immune responses in the brain and
meninges, but its molecular makeup among bones and relevance in human diseases remain …

MiRNAs, a family of small non‐coding RNAs, have emerged as novel post‐transcriptional
regulators of numerous cellular responses. Although the involvement of miRNAs in the …

Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome
coronavirus type 2 (SARS-CoV-2), has been associated mainly with a range of neurological …

Background Microglia recognize pathogen-associated molecular patterns such as double-stranded
RNA (dsRNA) present in some viruses. Polyinosinic-polycytidylic acid [poly(I:C)] is a …

Neuroinflammation and oxidative stress are conditions leading to neurological and neuropsychiatric
disorders. Natural compounds exerting anti-inflammatory and anti-oxidative effects, …

The meninges of the brain are an important component of neuroinflammatory response. Diverse
immune cells move from the calvaria marrow into the dura mater via recently discovered …

Spatial molecular profiling of complex tissues is essential to investigate cellular function in
physiological and pathological states. However, methods for molecular analysis of biological …

Targeting nanoparticle therapeutics with cellular accuracy in whole organisms could open
breakthrough opportunities in precision medicine. However, evaluating and fine-tuning the …