User profiles for Haruka Ozaki
 | Haruka OzakiBioinformatics Laboratory, Faculty of Medicine, University of Tsukuba Verified email at md.tsukuba.ac.jp Cited by 1013 |
[HTML][HTML] Single-cell full-length total RNA sequencing uncovers dynamics of recursive splicing and enhancer RNAs
T Hayashi, H Ozaki, Y Sasagawa, M Umeda… - Nature …, 2018 - nature.com
Total RNA sequencing has been used to reveal poly(A) and non-poly(A) RNA expression,
RNA processing and enhancer activity. To date, no method for full-length total RNA …
RNA processing and enhancer activity. To date, no method for full-length total RNA …
CLOCK-controlled polyphonic regulation of circadian rhythms through canonical and noncanonical E-boxes
In mammalian circadian clockwork, the CLOCK-BMAL1 complex binds to DNA enhancers of
target genes and drives circadian oscillation of transcription. Here we identified 7,978 …
target genes and drives circadian oscillation of transcription. Here we identified 7,978 …
ADARB1 catalyzes circadian A-to-I editing and regulates RNA rhythm
H Terajima, H Yoshitane, H Ozaki, Y Suzuki… - Nature …, 2017 - nature.com
It has been proposed that the CLOCK–ARNTL (BMAL1) complex drives circadian transcription
of thousands of genes, including Per and Cry family genes that encode suppressors of …
of thousands of genes, including Per and Cry family genes that encode suppressors of …
[HTML][HTML] Functional D-box sequences reset the circadian clock and drive mRNA rhythms
The circadian clock drives gene expression rhythms, leading to daily changes in physiology
and behavior. In mammals, Albumin D-site-Binding Protein (DBP) rhythmically activates …
and behavior. In mammals, Albumin D-site-Binding Protein (DBP) rhythmically activates …
[PDF][PDF] Somatic primary piRNA biogenesis driven by cis-acting RNA elements and trans-acting Yb
Primary piRNAs in Drosophila ovarian somatic cells arise from piRNA cluster transcripts and
the 3′ UTRs of a subset of mRNAs, including Traffic jam (Tj) mRNA. However, it is unclear …
the 3′ UTRs of a subset of mRNAs, including Traffic jam (Tj) mRNA. However, it is unclear …
[HTML][HTML] CapR: revealing structural specificities of RNA-binding protein target recognition using CLIP-seq data
RNA-binding proteins (RBPs) bind to their target RNA molecules by recognizing specific
RNA sequences and structural contexts. The development of CLIP-seq and related protocols …
RNA sequences and structural contexts. The development of CLIP-seq and related protocols …
[PDF][PDF] Integrated analysis of glycan and RNA in single cells
Single-cell sequencing has emerged as an indispensable technology to dissect cellular
heterogeneity but never been applied to the simultaneous analysis of glycan and RNA. Using …
heterogeneity but never been applied to the simultaneous analysis of glycan and RNA. Using …
[HTML][HTML] Possible cross-feeding pathway of facultative methylotroph Methyloceanibacter caenitepidi Gela4 on methanotroph Methylocaldum marinum S8
Non-methanotrophic bacteria such as methylotrophs often coexist with methane-oxidizing
bacteria (methanotrophs) by cross-feeding on methane-derived carbon. Methanol has long …
bacteria (methanotrophs) by cross-feeding on methane-derived carbon. Methanol has long …
[HTML][HTML] Discovery of osmotic sensitive transcription factors in fish intestine via a transcriptomic approach
Background Teleost intestine is crucial for seawater acclimation by sensing osmolality of
imbibed seawater and regulating drinking and water/ion absorption. Regulatory genes for …
imbibed seawater and regulating drinking and water/ion absorption. Regulatory genes for …
[PDF][PDF] Trans-omic analysis reveals obesity-associated dysregulation of inter-organ metabolic cycles between the liver and skeletal muscle
Systemic metabolic homeostasis is regulated by inter-organ metabolic cycles involving
multiple organs. Obesity impairs inter-organ metabolic cycles, resulting in metabolic diseases. …
multiple organs. Obesity impairs inter-organ metabolic cycles, resulting in metabolic diseases. …