User profiles for Harukazu Suzuki
harukazu suzukiGroup Director, RIKEN CLST Verified email at gsc.riken.jp Cited by 41159 |
A comprehensive survey of 3′ animal miRNA modification events and a possible role for 3′ adenylation in modulating miRNA targeting effectiveness
…, T Funakoshi, T Kurokawa, H Suzuki… - Genome …, 2010 - genome.cshlp.org
Animal microRNA sequences are subject to 3′ nucleotide addition. Through detailed analysis
of deep-sequenced short RNA data sets, we show adenylation and uridylation of miRNA …
of deep-sequenced short RNA data sets, we show adenylation and uridylation of miRNA …
An atlas of active enhancers across human cell types and tissues
Enhancers control the correct temporal and cell-type-specific activation of gene expression
in multicellular eukaryotes. Knowing their properties, regulatory activity and targets is crucial …
in multicellular eukaryotes. Knowing their properties, regulatory activity and targets is crucial …
Genome-wide analysis of mammalian promoter architecture and evolution
Mammalian promoters can be separated into two classes, conserved TATA box–enriched
promoters, which initiate at a well-defined site, and more plastic, broad and evolvable CpG-…
promoters, which initiate at a well-defined site, and more plastic, broad and evolvable CpG-…
Structural parts involved in activation and inactivation of the sodium channel
Abstract Structure–function relationships of the sodium channel expressed inXenopus
oocytes have been investigated by the combined use of site–directed mutagenesis and patch-…
oocytes have been investigated by the combined use of site–directed mutagenesis and patch-…
Enhanced identification of transcriptional enhancers provides mechanistic insights into diseases
Enhancers are distal cis-regulatory DNA elements that increase the expression of target
genes. Various experimental and computational approaches including chromatin signature …
genes. Various experimental and computational approaches including chromatin signature …
An atlas of human long non-coding RNAs with accurate 5′ ends
Long non-coding RNAs (lncRNAs) are largely heterogeneous and functionally uncharacterized.
Here, using FANTOM5 cap analysis of gene expression (CAGE) data, we integrate …
Here, using FANTOM5 cap analysis of gene expression (CAGE) data, we integrate …
Existence of distinct sodium channel messenger RNAs in rat brain
The sodium channel is a voltage-gated ionic channel essential for the generation of action
potentials 1–3 . It has been reported that the sodium channels purified from the electric organ …
potentials 1–3 . It has been reported that the sodium channels purified from the electric organ …
The regulated retrotransposon transcriptome of mammalian cells
…, H Takahashi, J Kawai, ARR Forrest, H Suzuki… - Nature …, 2009 - nature.com
Although repetitive elements pervade mammalian genomes, their overall contribution to
transcriptional activity is poorly defined. Here, as part of the FANTOM4 project, we report that 6–…
transcriptional activity is poorly defined. Here, as part of the FANTOM4 project, we report that 6–…
High-throughput mapping of a dynamic signaling network in mammalian cells
Signaling pathways transmit information through protein interaction networks that are
dynamically regulated by complex extracellular cues. We developed LUMIER (for luminescence-…
dynamically regulated by complex extracellular cues. We developed LUMIER (for luminescence-…
[HTML][HTML] An atlas of combinatorial transcriptional regulation in mouse and man
Combinatorial interactions among transcription factors are critical to directing tissue-specific
gene expression. To build a global atlas of these combinations, we have screened for …
gene expression. To build a global atlas of these combinations, we have screened for …