User profiles for Hassan S Dashti

Hassan S Dashti

Assistant Professor, Massachusetts General Hospital, Harvard Medical School
Verified email at mgh.harvard.edu
Cited by 7648

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

…, N Craddock, GE Crawford, CA Crowley, HS Dashti… - Nature …, 2018 - nature.com
Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …

[HTML][HTML] Short sleep duration and dietary intake: epidemiologic evidence, mechanisms, and health implications

HS Dashti, FAJL Scheer, PF Jacques, S Lamon-Fava… - Advances in …, 2015 - Elsevier
Links between short sleep duration and obesity, type 2 diabetes, hypertension, and cardiovascular
disease may be mediated through changes in dietary intake. This review provides an …

[HTML][HTML] Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms

…, J Tyrrell, RN Beaumont, AR Jeffries, HS Dashti… - Nature …, 2019 - nature.com
Being a morning person is a behavioural indicator of a person’s underlying circadian rhythm.
Using genome-wide data from 697,828 UK Biobank and 23andMe participants we …

Sleep characteristics across the lifespan in 1.1 million people from the Netherlands, United Kingdom and United States: a systematic review and meta-analysis

…, WJ Burk, HC Comijs, E Corpeleijn, HS Dashti… - Nature human …, 2021 - nature.com
We aimed to obtain reliable reference charts for sleep duration, estimate the prevalence of
sleep complaints across the lifespan and identify risk indicators of poor sleep. Studies were …

[HTML][HTML] Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates

HS Dashti, SE Jones, AR Wood, JM Lane… - Nature …, 2019 - nature.com
Sleep is an essential state of decreased activity and alertness but molecular factors regulating
sleep duration remain unknown. Through genome-wide association analysis in 446,118 …

Biological and clinical insights from genetics of insomnia symptoms

JM Lane, SE Jones, HS Dashti, AR Wood, KG Aragam… - Nature …, 2019 - nature.com
Insomnia is a common disorder linked with adverse long-term medical and psychiatric
outcomes. The underlying pathophysiological processes and causal relationships of insomnia …

Night shift work, genetic risk, and type 2 diabetes in the UK biobank

C Vetter, HS Dashti, JM Lane, SG Anderson… - Diabetes …, 2018 - Am Diabetes Assoc
OBJECTIVE To examine the effects of past and current night shift work and genetic type 2
diabetes vulnerability on type 2 diabetes odds. RESEARCH DESIGN AND METHODS In the …

[HTML][HTML] Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour

…, S Sabia, A van der Spek, HS Dashti… - Nature …, 2019 - nature.com
Sleep is an essential human function but its regulation is poorly understood. Using accelerometer
data from 85,670 UK Biobank participants, we perform a genome-wide association …

Sleep duration and myocardial infarction

I Daghlas, HS Dashti, J Lane, KG Aragam… - Journal of the American …, 2019 - jacc.org
Background : Observational studies suggest associations between extremes of sleep duration
and myocardial infarction (MI), but the causal contribution of sleep to MI and its potential to …

[HTML][HTML] Sleep apnea and COVID-19 mortality and hospitalization

…, HS Dashti, SM Hassan, S Redline… - American journal of …, 2020 - atsjournals.org
Methods The sample was adult nonemployee participants with positive COVID-19 RNA PCR
diagnostic results who had available demographic data, a minimum of two clinical notes, …