Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a
global pandemic in 2020. Testing is crucial for mitigating public health and economic effects. …

Escherichia coli and other Enterobacteriaceae are diverse species with “open” pangenomes,
where genes move intra- and interspecies via horizontal gene transfer. However, most …

Diagnosis of orthopedic device-related infection is challenging, and causative pathogens
may be difficult to culture. Metagenomic sequencing can diagnose infections without culture, …

F-type plasmids are diverse and of great clinical significance, often carrying genes conferring
antimicrobial resistance (AMR) such as extended-spectrum β-lactamases, particularly in …

Hybrid assemblies are highly valuable for studies of Enterobacteriaceae due to their ability to
fully resolve the structure of mobile genetic elements, such as plasmids, which are involved …

Mycobacterial cells elongate via polar deposition of cell wall material, similar to the filamentous
Streptomyces species, which contain a tip-organizing centre. Coiled-coiled proteins such …

Several bioinformatics genotyping algorithms are now commonly used to characterize
antimicrobial resistance (AMR) gene profiles in whole-genome sequencing (WGS) data, with a …

… Sophie George taught me how to perform ONT library prep and Hayleah Pickford how to
perform DNA extraction using the genomic tip method. Anthony Brown performed DNA …

Background Lateral flow device (LFD) viral antigen immunoassays have been developed
around the world as diagnostic tests for SARS-CoV-2 infection. They have been proposed to …

As the British summer quickly changes into autumn, we have been making on some changes
with the journal that should be worked through by the end of the year, as we start planning …