User profiles for Heath A. MacMillan
Heath A. MacMillanAssociate Professor, Carleton University Verified email at carleton.ca Cited by 3676 |
Mechanisms underlying insect chill-coma
HA MacMillan, BJ Sinclair - Journal of insect physiology, 2011 - Elsevier
At their critical thermal minimum (CT min ) insects enter chill-coma, a reversible state where
neuromuscular transmission and movement cease. The physiological mechanisms …
neuromuscular transmission and movement cease. The physiological mechanisms …
The integrative physiology of insect chill tolerance
J Overgaard, HA MacMillan - Annual review of physiology, 2017 - annualreviews.org
Cold tolerance is important in defining the distribution of insects. Here, we review the principal
physiological mechanisms underlying homeostatic failure during cold exposure in this …
physiological mechanisms underlying homeostatic failure during cold exposure in this …
Cross-tolerance and cross-talk in the cold: relating low temperatures to desiccation and immune stress in insects
…, G Salehipour-Shirazi, HA MacMillan - Integrative and …, 2013 - academic.oup.com
Multiple stressors, both abiotic and biotic, often are experienced simultaneously by organisms
in nature. Responses to these stressors may share signaling pathways (“cross-talk”) or …
in nature. Responses to these stressors may share signaling pathways (“cross-talk”) or …
How to assess Drosophila cold tolerance: chill coma temperature and lower lethal temperature are the best predictors of cold distribution limits
…, T Manenti, JG Sørensen, HA MacMillan… - Functional …, 2015 - Wiley Online Library
Thermal tolerance may limit and therefore predict ectotherm geographic distributions. However,
which of the many metrics of thermal tolerance best predict distribution is often unclear, …
which of the many metrics of thermal tolerance best predict distribution is often unclear, …
The role of the gut in insect chilling injury: cold-induced disruption of osmoregulation in the fall field cricket, Gryllus pennsylvanicus
HA MacMillan, BJ Sinclair - Journal of Experimental Biology, 2011 - journals.biologists.com
To predict the effects of changing climates on insect distribution and abundance, a clear
understanding of the mechanisms that underlie critical thermal limits is required. In insects, the …
understanding of the mechanisms that underlie critical thermal limits is required. In insects, the …
[HTML][HTML] Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome
HA MacMillan, JM Knee, AB Dennis, H Udaka… - Scientific Reports, 2016 - nature.com
Cold tolerance is a key determinant of insect distribution and abundance, and thermal
acclimation can strongly influence organismal stress tolerance phenotypes, particularly in small …
acclimation can strongly influence organismal stress tolerance phenotypes, particularly in small …
Reestablishment of ion homeostasis during chill-coma recovery in the cricket Gryllus pennsylvanicus
HA MacMillan, CM Williams… - Proceedings of the …, 2012 - National Acad Sciences
The time required to recover from cold-induced paralysis (chill-coma) is a common measure
of insect cold tolerance used to test central questions in thermal biology and predict the …
of insect cold tolerance used to test central questions in thermal biology and predict the …
[HTML][HTML] Thermal variability increases the impact of autumnal warming and drives metabolic depression in an overwintering butterfly
Increases in thermal variability elevate metabolic rate due to Jensen's inequality, and increased
metabolic rate decreases the fitness of dormant ectotherms by increasing consumption …
metabolic rate decreases the fitness of dormant ectotherms by increasing consumption …
[HTML][HTML] The capacity to maintain ion and water homeostasis underlies interspecific variation in Drosophila cold tolerance
Many insects, including Drosophila, succumb to the physiological effects of chilling at
temperatures well above those causing freezing. Low temperature causes a loss of extracellular …
temperatures well above those causing freezing. Low temperature causes a loss of extracellular …
Real-time measurement of metabolic rate during freezing and thawing of the wood frog, Rana sylvatica: implications for overwinter energy use
…, CM Williams, HA MacMillan… - Journal of …, 2013 - journals.biologists.com
Ectotherms overwintering in temperate ecosystems must survive low temperatures while
conserving energy to fuel post-winter reproduction. Freeze-tolerant wood frogs, Rana sylvatica, …
conserving energy to fuel post-winter reproduction. Freeze-tolerant wood frogs, Rana sylvatica, …