Caloric restriction (CR), without malnutrition, delays aging and extends life span in diverse
species; however, its effect on resistance to illness and mortality in primates has not been …

Infection with Asian-lineage Zika virus (ZIKV) has been associated with Guillain–Barré
syndrome and fetal abnormalities, but the underlying mechanisms remain poorly understood. …

Infection with Zika virus (ZIKV) is associated with human congenital fetal anomalies. To
model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV …

Background Activation of the peroxisome proliferator-activated receptor gamma (PPAR-γ)
has been proposed as a possible neuroprotective strategy to slow down the progression of …

Zika virus (ZIKV) infection is associated with congenital defects and pregnancy loss. Here,
we found that 26% of nonhuman primates infected with Asian/American ZIKV in early …

Congenital Zika virus (ZIKV) infection impacts fetal development and pregnancy outcomes.
We infected a pregnant rhesus macaque with a Puerto Rican ZIKV isolate in the first trimester…

Endometriosis is a common chronic inflammatory condition causing pelvic pain and infertility
in women, with limited treatment options and 50% heritability. We leveraged genetic …

Congenital Zika virus (ZIKV) infection was first linked to birth defects during the American
outbreak in 2015/2016. It has been proposed that mutations unique to the Asian/American-…

Zika virus (ZIKV) infection during pregnancy causes congenital abnormalities, including
microcephaly. However, rates vary widely, and the contributing risk factors remain unclear. We …

Glial cell line derived neurotrophic factor (GDNF) is a neurotrophic factor that has neuroprotective
effects in animal models of Parkinson’s disease (PD) and has been proposed as a PD …