Ducks: the “Trojan horses” of H5N1 influenza
JK Kim, NJ Negovetich, HL Forrest… - Influenza and other …, 2009 - Wiley Online Library
Wild ducks are the main reservoir of influenza A viruses that can be transmitted to domestic
poultry and mammals, including humans. Of the 16 hemagglutinin (HA) subtypes of influenza …
poultry and mammals, including humans. Of the 16 hemagglutinin (HA) subtypes of influenza …
Hemagglutinin–neuraminidase balance confers respiratory-droplet transmissibility of the pandemic H1N1 influenza virus in ferrets
HL Yen, CH Liang, CY Wu, HL Forrest… - Proceedings of the …, 2011 - National Acad Sciences
A novel reassortant derived from North American triple-reassortant (TRsw) and Eurasian
swine (EAsw) influenza viruses acquired sustained human-to-human transmissibility and …
swine (EAsw) influenza viruses acquired sustained human-to-human transmissibility and …
Adaptation of pandemic H1N1 influenza viruses in mice
…, AM Khalenkov, JP Seiler, HL Forrest… - Journal of …, 2010 - Am Soc Microbiol
The molecular mechanism by which pandemic 2009 influenza A viruses were able to
sufficiently adapt to humans is largely unknown. Subsequent human infections with novel H1N1 …
sufficiently adapt to humans is largely unknown. Subsequent human infections with novel H1N1 …
[HTML][HTML] A comparative analysis of host responses to avian influenza infection in ducks and chickens highlights a role for the interferon-induced transmembrane …
…, N Smith, L Yu, IR Paton, MW Gutowska, HL Forrest… - BMC genomics, 2015 - Springer
Background Chickens are susceptible to infection with a limited number of Influenza A
viruses and are a potential source of a human influenza pandemic. In particular, H5 and H7 …
viruses and are a potential source of a human influenza pandemic. In particular, H5 and H7 …
Puzzling inefficiency of H5N1 influenza vaccines in Egyptian poultry
…, G Kayali, D Walker, HL Forrest… - Proceedings of the …, 2010 - National Acad Sciences
In Egypt, efforts to control highly pathogenic H5N1 avian influenza virus in poultry and in
humans have failed despite increased biosecurity, quarantine, and vaccination at poultry farms. …
humans have failed despite increased biosecurity, quarantine, and vaccination at poultry farms. …
[HTML][HTML] The quail genome: insights into social behaviour, seasonal biology and infectious disease response
Background The Japanese quail (Coturnix japonica) is a popular domestic poultry species
and an increasingly significant model species in avian developmental, behavioural and …
and an increasingly significant model species in avian developmental, behavioural and …
Pathogenicity and vaccine efficacy of different clades of Asian H5N1 avian influenza A viruses in domestic ducks
JK Kim, P Seiler, HL Forrest, AM Khalenkov… - Journal of …, 2008 - Am Soc Microbiol
Waterfowl represent the natural reservoir of all subtypes of influenza A viruses, including
H5N1. Ducks are especially considered major contributors to the spread of H5N1 influenza A …
H5N1. Ducks are especially considered major contributors to the spread of H5N1 influenza A …
Perspectives on influenza evolution and the role of research
HL Forrest, RG Webster - Animal Health Research Reviews, 2010 - cambridge.org
Influenza is a highly contagious respiratory pathogen that continues to evolve and threaten
both veterinary and human public health. Influenza A viruses are continually undergoing …
both veterinary and human public health. Influenza A viruses are continually undergoing …
Virus shedding and potential for interspecies waterborne transmission of highly pathogenic H5N1 influenza virus in sparrows and chickens
HL Forrest, JK Kim, RG Webster - Journal of virology, 2010 - Am Soc Microbiol
To elucidate the role of sparrows as intermediate hosts of highly pathogenic avian influenza
H5N1 viruses, we assessed shedding and interspecies waterborne transmission of A/duck/…
H5N1 viruses, we assessed shedding and interspecies waterborne transmission of A/duck/…
Single-and multiple-clade influenza A H5N1 vaccines induce cross protection in ferrets
HL Forrest, AM Khalenkov, EA Govorkova, JK Kim… - Vaccine, 2009 - Elsevier
The rapid evolution, genetic diversity, broad host range, and increasing human infection with
avian influenza A (H5N1) viruses highlight the need for an efficacious cross-clade vaccine. …
avian influenza A (H5N1) viruses highlight the need for an efficacious cross-clade vaccine. …