Background The involvement of epigenetic mechanisms in intergenerational transmission
of stress effects has been demonstrated in animals but not in humans. Methods Cytosine …

Objective Differential effects of maternal and paternal posttraumatic stress disorder (PTSD)
have been observed in adult offspring of Holocaust survivors in both glucocorticoid receptor …

Intergenerational effects of trauma have been observed clinically in a wide range of populations,
and parental PTSD has been associated with an increased risk for psychopathology in …

Post-traumatic stress disorder (PTSD) can develop following severe trauma, but the extent
to which genetic and environmental risk factors contribute to individual clinical outcomes is …

Objective: There is growing evidence that exposure to trauma prior to conception can affect
offspring. The authors have reported that adult offspring of Holocaust survivors showed lower …

Background Adult offspring of Holocaust survivors comprise an informative cohort in which
to study intergenerational transmission of the effects of trauma exposure. Lower cortisol and …

Offspring of trauma survivors are more likely to develop PTSD, mood, and anxiety disorders
and demonstrate endocrine and molecular alterations compared to controls. This study …

Post-traumatic stress disorder (PTSD) is a condition of stress reactivity, whose clinical
manifestations are evident when patients are triggered following exposure to a traumatic event. …

Objective Cognitive behavioral therapies such as Prolonged Exposure (PE) are considered
first line treatments for posttraumatic stress disorder (PTSD). Nonetheless, many continue to …

Background: Parental traumatization has been associated with increased risk for the
expression of psychopathology in offspring, and maternal posttraumatic stress disorder (PTSD) …