User profiles for Heather T. Whittaker
 | Heather T. WhittakerMcGill University Verified email at mail.mcgill.ca Cited by 461 |
Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP
…, X Choong, JL Tosh, C Siganporia, HT Whittaker… - Brain, 2018 - academic.oup.com
Down syndrome, caused by trisomy of chromosome 21, is the single most common risk factor
for early-onset Alzheimer’s disease. Worldwide approximately 6 million people have Down …
for early-onset Alzheimer’s disease. Worldwide approximately 6 million people have Down …
[HTML][HTML] Multiple system atrophy: genetic risks and alpha-synuclein mutations
Multiple system atrophy (MSA) is one of the few neurodegenerative disorders where we have
a significant understanding of the clinical and pathological manifestations but where the …
a significant understanding of the clinical and pathological manifestations but where the …
[HTML][HTML] Information-based rhythmic transcranial magnetic stimulation to accelerate learning during auditory working memory training: a proof-of-concept study
HT Whittaker, L Khayyat, J Fortier-Lavallée… - Frontiers in …, 2024 - frontiersin.org
Introduction Rhythmic transcranial magnetic stimulation (rhTMS) has been shown to enhance
auditory working memory manipulation, specifically by boosting theta oscillatory power in …
auditory working memory manipulation, specifically by boosting theta oscillatory power in …
[HTML][HTML] Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models
JL Tosh, ER Rhymes, P Mumford, HT Whittaker… - Scientific Reports, 2021 - nature.com
Individuals who have Down syndrome (caused by trisomy of chromosome 21), have a greatly
elevated risk of early-onset Alzheimer’s disease, in which amyloid-β accumulates in the …
elevated risk of early-onset Alzheimer’s disease, in which amyloid-β accumulates in the …
T1, diffusion tensor, and quantitative magnetization transfer imaging of the hippocampus in an Alzheimer's disease mouse model
HT Whittaker, S Zhu, DL Di Curzio, R Buist… - Magnetic resonance …, 2018 - Elsevier
Alzheimer's disease (AD) pathology causes microstructural changes in the brain. These
changes, if quantified with magnetic resonance imaging (MRI), could be studied for use as an …
changes, if quantified with magnetic resonance imaging (MRI), could be studied for use as an …
An exercise in scientific writing for physicians in training
It is important to strengthen critical thinking and scientific writing abilities during medical
training to support trainees in their research endeavors and prepare students for careers in …
training to support trainees in their research endeavors and prepare students for careers in …
[HTML][HTML] The effects of Cstb duplication on APP/amyloid-β pathology and cathepsin B activity in a mouse model
Y Wu, HT Whittaker, S Noy, K Cleverley, V Brault… - Plos one, 2021 - journals.plos.org
People with Down syndrome (DS), caused by trisomy of chromosome 21 have a greatly
increased risk of developing Alzheimer’s disease (AD). This is in part because of triplication of a …
increased risk of developing Alzheimer’s disease (AD). This is in part because of triplication of a …
Overview of the Canadian Clinician Investigator Trainees' research presented at the 2019 CSCI-CITAC Joint Meeting
…, C Lefebvre, EK Cook, HT Whittaker… - Clinical and …, 2020 - utpjournals.press
The 2019 Annual General Meeting and Young Investigators’ Forum of the Canadian Society
for Clinical Investigation / Société Canadienne de Recherche Clinique (CSCI/SCRC) and …
for Clinical Investigation / Société Canadienne de Recherche Clinique (CSCI/SCRC) and …
[PDF][PDF] Therapy for spinal muscular atrophy
HT Whittaker, MA Michell-Robinson - N Engl J Med, 2018 - researchgate.net
To the Editor: In two reports regarding patients with type 1 spinal muscular atrophy (Nov. 2
issue), 1, 2 researchers describe therapies involving antisense oligonucleotides (Finkel et al.) …
issue), 1, 2 researchers describe therapies involving antisense oligonucleotides (Finkel et al.) …
Overview of the Canadian Clinician Investigator Trainees' research presented at CSCI-CITAC Joint Meeting
…, W Wang, AT Yuan, HT Whittaker - Clinical and …, 2022 - utpjournals.press
The 2021 Annual Joint Meeting (AJM) and Young Investigators’ Forum of the Canadian
Society for Clinical Investigation / Société Canadienne de Recherches Clinique (CSCI/SCRC) …
Society for Clinical Investigation / Société Canadienne de Recherches Clinique (CSCI/SCRC) …