There is an increasing need for applications in food and environmental areas able to cope
with a large number of analytes in very complex matrices. The new analytical procedures …

In this study, we sought to determine whether asthma has a metabolic profile and whether
this profile is related to disease severity. We characterised the serum from 22 healthy …

Background: Cardiovascular risk in diabetes remains elevated despite glucose-lowering
therapies. We hypothesized that hyperglycemia induces trained immunity in macrophages, …

Background Metabolic alterations, related to cerebral glucose metabolism, brain insulin
resistance, and age-induced mitochondrial dysfunction, play an important role in Alzheimer’s …

The supply of safe and high-quality foodstuffs relies on the efficient protection of food from
deterioration. However, all food-packaging materials can release small amounts of their …

Chronic inflammation triggers compensatory immunosuppression to stop inflammation and
minimize tissue damage. Studies have demonstrated that endoplasmic reticulum (ER) stress …

Tumor-associated macrophages (TAMs) display pro-tumorigenic phenotypes for supporting
tumor progression in response to microenvironmental cues imposed by tumor and stromal …

Immunoediting sculpts immunogenicity and thwarts host anti-tumor responses in tumor cells
during tumorigenesis; however, it remains unknown whether metabolic programming of …

Extracellular vesicles (EVs), including exosomes, modulate multiple aspects of cancer biology.
Tumor-associated macrophages (TAMs) secrete EVs, but their molecular features and …

High-resolution mass spectrometry (HRMS)-based metabolomics approaches have made
significant advances. However, metabolite identification is still a major challenge with …