Online application for survival analysis (OASIS) has served as a popular and convenient
platform for the statistical analysis of various survival data, particularly in the field of aging …

Cancer patient classification using predictive biomarkers for anti-cancer drug responses is
essential for improving therapeutic outcomes. However, current machine-learning-based …

Adult stem cells constantly react to local changes to ensure tissue homeostasis. In the main
body of the stomach, chief cells produce digestive enzymes; however, upon injury, they …

Background Previous investigations of transcriptomic signatures of cancer patient survival
and post-therapy relapse have focused on tumor tissue. In contrast, here we show that in …

Mice have been widely used as a model organism to investigate human gene–phenotype
relationships based on a conjecture that orthologous genes generally perform similar …

The modular architecture of protein-protein interaction (PPI) networks is evident in diverse
species with a wide range of complexity. However, the molecular components that lead to the …

The mammalian intestine is one of the most rapidly self-renewing tissues, driven by stem
cells residing at the crypt bottom. Paneth cells form a major element of the niche …

Background Traditional Korean Sasang constitutional (SC) medicine categorizes individuals
into four constitutional types [Tae-eum (TE), So-eum (SE), Tae-yang (TY), or So-yang (SY)] …

Recent studies have shed light on the signaling pathways required for gastric tissue
maintenance and how aberrations in these key pathways lead to gastric cancer development. …

Identifying cancer type-specific driver mutations is crucial for illuminating distinct pathologic
mechanisms across various tumors and providing opportunities of patient-specific treatment. …