Uterosacral ligament in postmenopausal women with or without pelvic organ prolapse

B Gabriel, D Denschlag, H Göbel, C Fittkow… - International …, 2005 - Springer
The uterosacral ligaments are thought to contribute to pelvic support. The objective of this
study was to compare the structural components of these ligaments in women with and without …

Reduction of the aortic inflammatory response in spontaneous atherosclerosis by blockade of macrophage migration inhibitory factor (MIF)

A Burger-Kentischer, H Göbel, R Kleemann… - Atherosclerosis, 2006 - Elsevier
Atherosclerosis is an inflammatory response of the arterial wall to “injury”, which is prominently
driven by cytokines. The inflammatory mediator macrophage migration inhibitory factor (…

[HTML][HTML] First report from the German COVID-19 autopsy registry

…, D Horst, S Elezkurtaj, A Quaas, H Göbel… - The Lancet Regional …, 2022 - thelancet.com
Background Autopsies are an important tool in medicine, dissecting disease pathophysiology
and causes of death. In COVID-19, autopsies revealed eg, the effects on pulmonary (micro…

STAT3 mRNA and protein expression in colorectal cancer: effects on STAT3-inducible targets linked to cell survival and proliferation

S Lassmann, I Schuster, A Walch, H Göbel… - Journal of clinical …, 2007 - jcp.bmj.com
Aims: To evaluate mRNA and protein expression of signal transducers and activators of
transcription (STAT)3 in colorectal carcinomas (CRCs) and to define the association of STAT3 …

Mutations in NEK8 link multiple organ dysplasia with altered Hippo signalling and increased c-MYC expression

…, C Decker, RAC Boorsma, H Göbel… - Human molecular …, 2013 - academic.oup.com
Mutations affecting the integrity and function of cilia have been identified in various genes
over the last decade accounting for a group of diseases called ciliopathies. Ciliopathies …

[HTML][HTML] Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies?

…, F Fend, N Gaßler, S Gattenlöhner, M Glatzel, H Göbel… - Virchows Archiv, 2022 - Springer
The use of autopsies in medicine has been declining. The COVID-19 pandemic has
documented and rejuvenated the importance of autopsies as a tool of modern medicine. In this …

High Prevalence of Circulating CD4+CD28 T-Cells in Patients With Small Abdominal Aortic Aneurysms

C Duftner, R Seiler, P Klein-Weigel… - … , and vascular biology, 2005 - Am Heart Assoc
Objective— To assess the possible role of proinflammatory CD28 − T cells in abdominal aortic
aneurysms (AAAs). Animal studies and human tissue studies suggest a role for interferon (…

[HTML][HTML] Sphingosine 1-phosphate protects ovaries from chemotherapy-induced damage in vivo

K Hancke, O Strauch, C Kissel, H Göbel, W Schäfer… - Fertility and sterility, 2007 - Elsevier
OBJECTIVE: To investigate whether sphingosine-1-phosphate (S1P), an apoptosis-inhibitor,
would be able to protect ovarian follicles from chemotherapy-induced cell death in vivo. …

Hyperoxaluria and systemic oxalosis: an update on current therapy and future directions

BB Beck, H Hoyer-Kuhn, H Göbel… - Expert opinion on …, 2013 - Taylor & Francis
Introduction: The primary hyperoxalurias (PH) are rare, but underdiagnosed disorders
where the loss of enzymatic activity in key compounds of glyoxylate metabolism results in …

YAP-mediated mechanotransduction determines the podocyte's response to damage

…, H Hagmann, O Kretz, S Bertsch, M Höhne, H Göbel… - Science …, 2017 - science.org
Podocytes are terminally differentiated cells of the kidney filtration barrier. They are subjected
to physiological filtration pressure and considerable mechanical strain, which can be …