User profiles for Helen Leonard
 | Helen LeonardAssociate Professor, Centre for Child Health Research, University of Western Australia Verified email at telethonkids.org.au Cited by 22159 |
Rett syndrome: revised diagnostic criteria and nomenclature
…, AJ Clarke, N Bahi‐Buisson, H Leonard… - Annals of …, 2010 - Wiley Online Library
Objective Rett syndrome (RTT) is a severe neurodevelopmental disease that affects
approximately 1 in 10,000 live female births and is often caused by mutations in Methyl‐CpG‐…
approximately 1 in 10,000 live female births and is often caused by mutations in Methyl‐CpG‐…
The epidemiology of mental retardation: challenges and opportunities in the new millennium
H Leonard, X Wen - Mental retardation and developmental …, 2002 - Wiley Online Library
There are a number of problems and challenges in relating the science of epidemiology to
mental retardation (MR). These relate to how MR is defined and classified and how these …
mental retardation (MR). These relate to how MR is defined and classified and how these …
[PDF][PDF] Mutations of CDKL5 cause a severe neurodevelopmental disorder with infantile spasms and mental retardation
Rett syndrome (RTT) is a severe neurodevelopmental disorder caused, in most classic cases,
by mutations in the X-linked methyl-CpG-binding protein 2 gene (MECP2). A large degree …
by mutations in the X-linked methyl-CpG-binding protein 2 gene (MECP2). A large degree …
Association of genetic and environmental factors with autism in a 5-country cohort
Importance The origins and development of autism spectrum disorder (ASD) remain
unresolved. No individual-level study has provided estimates of additive genetic, maternal, and …
unresolved. No individual-level study has provided estimates of additive genetic, maternal, and …
Intellectual disability co-occurring with schizophrenia and other psychiatric illness: population-based study
VA Morgan, H Leonard, J Bourke… - The British Journal of …, 2008 - cambridge.org
BackgroundThe epidemiology of intellectual disability co-occurring with schizophrenia and
other psychiatric illness is poorly understood. The separation of mental health from …
other psychiatric illness is poorly understood. The separation of mental health from …
Rett syndrome in Australia: a review of the epidemiology
…, D Ravine, C Ellaway, S Williamson, H Leonard - The Journal of …, 2006 - Elsevier
OBJECTIVE: To examine the prevalence, cumulative incidence, and survival in an
Australian cohort with Rett syndrome (RTT). STUDY DESIGN: The Australian Rett Syndrome …
Australian cohort with Rett syndrome (RTT). STUDY DESIGN: The Australian Rett Syndrome …
Long-read sequence analysis of the MECP2 gene in Rett syndrome patients: correlation of disease severity with mutation type and location
…, J Maynard, A Kerr, H Leonard… - Human molecular …, 2000 - academic.oup.com
Mutations in the methyl-CpG-binding protein gene MECP2 at Xq28 cause Rett syndrome (RTT),
an X-linked dominant neurodevelopmental disorder characterized by a period of …
an X-linked dominant neurodevelopmental disorder characterized by a period of …
The increasing prevalence of reported diagnoses of childhood psychiatric disorders: a descriptive multinational comparison
The objective of this study is to compare the time trend of reported diagnoses of autism
spectrum disorder (ASD), hyperkinetic disorder, Tourette’s syndrome, and obsessive-compulsive …
spectrum disorder (ASD), hyperkinetic disorder, Tourette’s syndrome, and obsessive-compulsive …
[HTML][HTML] Autism risk associated with parental age and with increasing difference in age between the parents
Advancing paternal and maternal age have both been associated with risk for autism spectrum
disorders (ASD). However, the shape of the association remains unclear, and results on …
disorders (ASD). However, the shape of the association remains unclear, and results on …
[HTML][HTML] The CDKL5 disorder is an independent clinical entity associated with early-onset encephalopathy
…, S Psoni, X Bao, N De Klerk, H Leonard… - European Journal of …, 2013 - nature.com
The clinical understanding of the CDKL5 disorder remains limited, with most information
being derived from small patient groups seen at individual centres. This study uses a large …
being derived from small patient groups seen at individual centres. This study uses a large …