Hedgehog ligands control tissue development and homeostasis by alleviating repression of
Smoothened, a seven-pass transmembrane protein. The Hedgehog receptor, Patched, is …

Hedgehog (Hh) is a lipoprotein-borne ligand that regulates both patterning and proliferation
in a wide variety of vertebrate and invertebrate tissues. When Hh is absent, its receptor …

Abstract Changes in cell metabolism and plasma membrane potential have been linked to
shifts between tissue growth and differentiation, and to developmental patterning. How such …

At a cellular level, nutrients are sensed by the mechanistic Target of Rapamycin (mTOR).
The response of cells to hypoxia is regulated via action of the oxygen sensor Hypoxia-Inducible …

The authors regret omitting the citation of a bioRxiv preprint study by preprint: Emmons-Bell
et al (2020), who independently discovered the role of ion channel-dependent membrane …

Hedgehog proteins are lipid-modified secreted signaling molecules that regulate tissue
development and homeostasis. Lipids contained in circulating lipoproteins repress the …

Here, we introduce a novel system for hypoxia induction, which we developed to study the
effects of hypoxia in aquatic organisms such as frog and zebrafish embryos. Our system …

The LIPID MAPS meeting features two poster sessions with 55 posters. Of these posters,
four were selected for short talks this year (see program). We received so many high quality, …

(EN) Hedgehog is a lipid-linked morphogen that is carried on lipoprotein particles and that
regulates both patterning and proliferation in a wide variety of vertebrate and invertebrate …

Background Lipids are stored within cells in lipid droplets (LDs). They consist of a core of
neutral lipids surrounded by a monolayer of phospholipids, predominantly phosphatidylcholine …