User profiles for Helena Pivonkova

Helena Pivonkova

Department of Physiology, Second Faculty of Medicine, Charles University
Verified email at lfmotol.cuni.cz
Cited by 979

Periods of synchronized myelin changes shape brain function and plasticity

O de Faria Jr, H Pivonkova, B Varga, S Timmler… - Nature …, 2021 - nature.com
Myelin, a lipid membrane that wraps axons, enabling fast neurotransmission and metabolic
support to axons, is conventionally thought of as a static structure that is set early in …

Impact of global cerebral ischemia on K+ channel expression and membrane properties of glial cells in the rat hippocampus

H Pivonkova, J Benesova, O Butenko, A Chvatal… - Neurochemistry …, 2010 - Elsevier
Astrocytes and NG2 glia respond to CNS injury by the formation of a glial scar. Since the
changes in K + currents in astrocytes and NG2 glia that accompany glial scar formation might …

[PDF][PDF] Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence

…, S Buller, D Nuzzaci, K Ridley, B Lam, H Pivonkova… - Cell reports, 2021 - cell.com
The mediobasal hypothalamus (MBH; arcuate nucleus of the hypothalamus [ARH] and
median eminence [ME]) is a key nutrient sensing site for the production of the complex …

Transplantation of predifferentiated adipose-derived stromal cells for the treatment of spinal cord injury

…, D Marekova, T Amemori, H Pivonkova… - Cellular and molecular …, 2011 - Springer
Adipose-derived stromal cells (ASCs) are an alternative source of stem cells for cell-based
therapies of neurological disorders such as spinal cord injury (SCI). In the present study, we …

Cell death/proliferation and alterations in glial morphology contribute to changes in diffusivity in the rat hippocampus after hypoxia—ischemia

M Anderova, I Vorisek, H Pivonkova… - Journal of Cerebral …, 2011 - journals.sagepub.com
To understand the structural alterations that underlie early and late changes in hippocampal
diffusivity after hypoxia/ischemia (H/I), the changes in apparent diffusion coefficient of water (…

[HTML][HTML] Distinct expression/function of potassium and chloride channels contributes to the diverse volume regulation in cortical astrocytes of GFAP/EGFP mice

J Benesova, V Rusnakova, P Honsa, H Pivonkova… - PLoS …, 2012 - journals.plos.org
Recently, we have identified two astrocytic subpopulations in the cortex of GFAP-EGFP mice,
in which the astrocytes are visualized by the enhanced green–fluorescent protein (EGFP) …

[HTML][HTML] Polydendrocytes display large lineage plasticity following focal cerebral ischemia

P Honsa, H Pivonkova, D Dzamba, M Filipova… - PLoS …, 2012 - journals.plos.org
Polydendrocytes (also known as NG2 glial cells) constitute a fourth major glial cell type in
the adult mammalian central nervous system (CNS) that is distinct from other cell types. …

A matter of state: diversity in oligodendrocyte lineage cells

Y Kamen, H Pivonkova, KA Evans… - The …, 2022 - journals.sagepub.com
Oligodendrocyte precursor cells (OPCs) give rise to oligodendrocytes which myelinate
axons in the central nervous system. Although classically thought to be a homogeneous …

Neuronal activity-dependent myelin repair after stroke

W Jia, Y Kamen, H Pivonkova, RT Káradóttir - Neuroscience letters, 2019 - Elsevier
Brain tissue undergoes substantial activity-dependent reorganisation after stroke due to
neuronal plasticity, leading to partial functional recovery in patients. Concurrent myelin repair is …

Increased expression of hyperpolarization‐activated cyclic nucleotide‐gated (HCN) channels in reactive astrocytes following ischemia

P Honsa, H Pivonkova, L Harantova, O Butenko… - Glia, 2014 - Wiley Online Library
Astrocytes respond to ischemic brain injury by proliferation, the increased expression of
intermediate filaments and hypertrophy, which results in glial scar formation. In addition, they …