[HTML][HTML] Genome sequencing sheds light on the contribution of structural variants to Brassica oleracea diversification
Background Brassica oleracea includes several morphologically diverse, economically
important vegetable crops, such as the cauliflower and cabbage. However, genetic variants, …
important vegetable crops, such as the cauliflower and cabbage. However, genetic variants, …
[HTML][HTML] Cyclometalated iridium (III) complexes as lysosome-targeted photodynamic anticancer and real-time tracking agents
Stimuli-activatable photosensitizers (PSs) are highly desirable for photodynamic therapy (PDT)
to selectively demolish tumor cells. On the other hand, lysosomes are emerging as …
to selectively demolish tumor cells. On the other hand, lysosomes are emerging as …
Phosphorescent iridium (III)-bis-N-heterocyclic carbene complexes as mitochondria-targeted theranostic and photodynamic anticancer agents
Mitochondria-targeted compounds represent a promising approach to target tumors
selectively and overcome resistance to current anticancer therapies. In this work, three …
selectively and overcome resistance to current anticancer therapies. In this work, three …
[HTML][HTML] FTO suppresses glycolysis and growth of papillary thyroid cancer via decreasing stability of APOE mRNA in an N6-methyladenosine-dependent manner
…, T Zhang, D Zhang, W Dong, L Shao, L He, X Ji… - Journal of Experimental …, 2022 - Springer
Background N6-methyladenosine (m 6 A) modification is the most common chemical
modification in mammalian mRNAs, and it plays important roles by regulating several cellular …
modification in mammalian mRNAs, and it plays important roles by regulating several cellular …
Theranostic iridium (III) complexes as one‐and two‐photon phosphorescent trackers to monitor autophagic lysosomes
…, RR Ye, YZ Zhao, YH Liu, Q Zhao, LN Ji… - Angewandte …, 2014 - Wiley Online Library
During autophagy, the intracellular components are captured in autophagosomes and
delivered to lysosomes for degradation and recycling. Changes in lysosomal trafficking and …
delivered to lysosomes for degradation and recycling. Changes in lysosomal trafficking and …
[HTML][HTML] Monitoring mitochondrial viscosity with anticancer phosphorescent Ir (III) complexes via two-photon lifetime imaging
…, DY Zhang, L He, W Liu, J Yang, CP Tan, LN Ji… - Chemical …, 2019 - pubs.rsc.org
Precise quantitative measurement of viscosity at the subcellular level presents great challenges.
Two-photon phosphorescence lifetime imaging microscopy (TPPLIM) can reflect micro-…
Two-photon phosphorescence lifetime imaging microscopy (TPPLIM) can reflect micro-…
Delivery of Phosphorescent Anticancer Iridium (III) Complexes by Polydopamine Nanoparticles for Targeted Combined Photothermal‐Chemotherapy and Thermal …
…, JH Sun, CP Tan, L He, W Zhang, LN Ji… - Advanced …, 2018 - Wiley Online Library
Recently, phosphorescent iridium complexes have demonstrated great potential as anticancer
and imaging agents. Dopamine is a melanin‐like mimic of mussel adhesive protein that …
and imaging agents. Dopamine is a melanin‐like mimic of mussel adhesive protein that …
Cyclometalated Ir (III) complexes as targeted theranostic anticancer therapeutics: combining HDAC inhibition with photodynamic therapy
RR Ye, CP Tan, L He, MH Chen, LN Ji… - Chemical …, 2014 - pubs.rsc.org
The successful design and anticancer mechanistic studies of a series of cyclometalated Ir
(III) complexes with histone deacetylase inhibitory and photodynamic therapy (PDT) …
(III) complexes with histone deacetylase inhibitory and photodynamic therapy (PDT) …
Cyclometalated iridium (iii) complexes induce mitochondria-derived paraptotic cell death and inhibit tumor growth in vivo
The development of iridium complexes as potent anticancer agents has received increasing
attention in recent years. In this study, four cyclometalated Ir(III) complexes with good …
attention in recent years. In this study, four cyclometalated Ir(III) complexes with good …
Three-Dimensional Topological Insulator Bi2Te3/Organic Thin Film Heterojunction Photodetector with Fast and Wideband Response from 450 to 3500 Nanometers
In the pursuit of broadband photodetection materials from visible to mid-IR region, the fresh
three-dimensional topological insulators (3D TIs) are theoretically predicted to be a …
three-dimensional topological insulators (3D TIs) are theoretically predicted to be a …