Hierarchical and redundant roles of activating FcγRs in protection against influenza disease by M2e-specific IgG1 and IgG2a antibodies

…, A Kolpe, K El Bakkouri, L Deng, H Grootaert… - Journal of …, 2017 - Am Soc Microbiol
The ectodomain of matrix protein 2 is a universal influenza A virus vaccine candidate that
provides protection through antibody-dependent effector mechanisms. Here we compared the …

Functional exploration of the GH29 fucosidase family

H Grootaert, L Van Landuyt, P Hulpiau… - …, 2020 - academic.oup.com
The deoxy sugar l-fucose is frequently found as a glycan constituent on and outside living
cells, and in mammals it is involved in a wide range of biological processes including …

[HTML][HTML] OPENPichia: licence-free Komagataella phaffii chassis strains and toolkit for protein expression

…, S Vanmarcke, E Çıtak, D Fijalkowska, H Grootaert… - Nature …, 2024 - nature.com
The industrial yeast Komagataella phaffii (formerly named Pichia pastoris) is commonly used
to synthesize recombinant proteins, many of which are used as human therapeutics or in …

[HTML][HTML] Endoglycosidase S enables a highly simplified clinical chemistry procedure for direct assessment of serum IgG undergalactosylation in chronic inflammatory …

…, L Meuris, T Raes, H Grootaert… - Molecular & cellular …, 2018 - ASBMB
Over the past 30 years, it has been firmly established that a wide spectrum of (autoimmune)
diseases such as rheumatoid arthritis, Crohn's and lupus, but also other pathologies like …

Yeast-produced fructosamine-3-kinase retains mobility after ex vivo intravitreal injection in human and bovine eyes as determined by Fluorescence Correlation …

AK Minnaert, L van Schie, H Grootaert, J Himpe… - International Journal of …, 2022 - Elsevier
… Author links open overlay panel An-Katrien Minnaert a 1 , Loes van Schie b c 1 , Hendrik
Grootaert b c , Jonas Himpe d , Simon Devos b c , Wannes Weyts b c , Herlinde De …

OPENPichia: building a free-to-operate Komagataella phaffii protein expression toolkit

…, B Van Moer, H Eeckhaut, D Fijalkowska, H Grootaert… - bioRxiv, 2022 - biorxiv.org
In the standard toolkit for recombinant protein expression, the yeast known in biotechnology
as Pichia pastoris (formally: Komagataella phaffii) takes up the position between E. coli and …

A simple colorimetric assay for measuring fructosamine 3 kinase activity

…, B Laukens, LV Schie, H Grootaert… - Clinical Chemistry and …, 2017 - degruyter.com
Background: Fructosamine 3 kinase (FN3K) is a deglycating enzyme, which may play a key
role in reducing diabetes-induced organ damage by removing bound glucose from glycated …

Clinical assay for direct assessment of IgG galactosylation in serum using endoglycosidase S

D Vanderschaeghe, L Meuris, H Grootaert, T Raes… - bioRxiv, 2018 - biorxiv.org
A wide spectrum of (autoimmune) diseases such as rheumatoid arthritis (RA), Crohn’s
disease, systemic lupus erythematosus, but also other pathologies such as alcoholic and non-…

[CITATION][C] Exploring glyco-active enzymes for biomedical glycan manipulation

H Grootaert - 2017 - biblio.ugent.be
… Author Hendrik Grootaert (UGent) … Grootaert H. Exploring glyco-active enzymes for
biomedical glycan manipulation. [Ghent, Belgium]: Ghent University. … Grootaert, “Exploring …

[PDF][PDF] Inventory of the Belgian bark beetles (Scolytidae), horned powderpost beetles (Bostrychidae) and their associated saproxylic beetle fauna

P Grootaert - data.inbo.be
Saproxylic beetles comprise an important part of forest biodiversity. Since many years there
is a great interest in saproxylophagous/xylobiont insects from various stakeholders. …