Epigenetic modifications, including DNA methylation, represent a potential mechanism for
environmental impacts on human disease. Maternal smoking in pregnancy remains an …

The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam
in The Netherlands. The study targets cardiovascular, endocrine, hepatic, neurological, …

The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam
in The Netherlands. The study targets cardiovascular, endocrine, hepatic, neurological, …

Coffee, a major dietary source of caffeine, is among the most widely consumed beverages in
the world and has received considerable attention regarding health risks and benefits. We …

Background The association of body mass index (BMI) with mortality remains controversial
among the middle-aged and elderly. Moreover, the contribution of other anthropometric …

Dutch’ figures on perinatal mortality and morbidity are poor compared to EU-standards.
Considerable within-country differences have been reported too, with decreased perinatal health …

Parental harsh disciplining, like corporal punishment, has consistently been associated with
adverse mental health outcomes in children. It remains a challenge to accurately assess the …

Background Sudden infant death syndrome (SIDS) is the unexpected death of an infant that
remains unexplained after a thorough investigation of the circumstances, family history, …

Background: Older adults grieving the death of a spouse have been found to have a higher
risk of complicated grief compared with younger adults. Objective: The study objective was to …

Objective: Disturbed sleep during pregnancy is associated with adverse obstetric outcomes
and less mental well-being. In pregnant women with a mental disorder, who frequently suffer …