Over the last decade, functionally designed DNA nanostructures applied to lipid membranes
prompted important achievements in the fields of biophysics and synthetic biology. Taking …

Peptide–membrane interactions have been gaining increased relevance, mainly in biomedical
investigation, as the potential of the natural, nature-based and synthetic peptides as new …

Reproduction, ie the ability to produce new individuals from a parent organism, is a hallmark
of living matter. Even the simplest forms of reproduction require cell division: attempts to …

Parkinson's disease (PD) is the most common representative of a group of disorders known
as synucleinopathies, in which misfolding and aggregation of α-synuclein (a-syn) in various …

The potential of antimicrobial peptides (AMPs) as an alternative to conventional therapies is
well recognized. Insights into the biological and biophysical properties of AMPs are thus key …

Autophagy is a catabolic pathway that sequesters undesired cellular material into autophagosomes
for delivery to lysosomes for degradation. A key step in the pathway is the covalent …

Hydrogel materials that display inherent activity against bacteria can be used to directly
treat accessible wounds to prevent or kill existing infection. Hydrogels composed of self-…

Cyclotides, a large family of cyclic peptides from plants, have a broad range of biological
activities, including insecticidal, cytotoxic, and anti-HIV activities. In all of these activities, cell …

Membrane sculpting and transformation is essential for many cellular functions, thus being
largely regulated by self-assembling and self-organizing protein coats. Their functionality is …

BP100 is a short cationic antimicrobial peptide with a mechanism of action dependent on
peptide–lipid interactions and microbial surface charge neutralization. Although active against …