Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis
…, S Boucherit, F Rozenberg, R Halwani, B Henry… - Nature medicine, 2019 - nature.com
… b, Family pedigrees with allele segregation in the five families. The patients (in black) are
heterozygous for the following mutations (V in red): V1 in kindreds A and B, V2 in kindred C, V3 …
heterozygous for the following mutations (V in red): V1 in kindreds A and B, V2 in kindred C, V3 …
Exquisitely specific anti-KRAS biodegraders inform on the cellular prevalence of nucleotide-loaded states
…, C Yeo, KM Peh, J Teo, S Ng, B Henry… - ACS central …, 2020 - ACS Publications
Mutations to RAS proteins (H-, N-, and K-RAS) are among the most common oncogenic
drivers, and tumors harboring these lesions are some of the most difficult to treat. Although …
drivers, and tumors harboring these lesions are some of the most difficult to treat. Although …
[HTML][HTML] Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis
Pulmonary edema associated with increased vascular permeability is a severe complication
of Staphylococcus aureus–induced sepsis and an important cause of human pathology and …
of Staphylococcus aureus–induced sepsis and an important cause of human pathology and …
The biosynthesis, structure and gelatinization properties of starches from wild and cultivated African rice species (Oryza barthii and Oryza glaberrima)
The molecular structure and gelatinization properties of starches from domesticated African
rice (Oryza glaberrima) and its wild progenitor (Oryza barthii) are determined and …
rice (Oryza glaberrima) and its wild progenitor (Oryza barthii) are determined and …
Expression of GM-CSF is regulated by Fli-1 transcription factor, a potential drug target
…, B Henry, S Schutt, XZ Yu, H Fan, W Zhang… - The Journal of …, 2021 - journals.aai.org
Friend leukemia virus integration 1 (Fli-1) is an ETS transcription factor and a critical regulator
of inflammatory mediators, including MCP-1, CCL5, IL-6, G-CSF, CXCL2, and caspase-1. …
of inflammatory mediators, including MCP-1, CCL5, IL-6, G-CSF, CXCL2, and caspase-1. …
[HTML][HTML] Phase II study of vemurafenib followed by ipilimumab in patients with previously untreated BRAF-mutated metastatic melanoma
…, SS Thomas, SJ O'Day, MF Shaheen, B Zhang… - … for immunotherapy of …, 2016 - Springer
Background Ipilimumab (IPI), an anti-CTLA-4 antibody, and vemurafenib (VEM), a BRAF
inhibitor, have distinct mechanisms of action and shared toxicities (eg, skin, gastrointestinal [GI] …
inhibitor, have distinct mechanisms of action and shared toxicities (eg, skin, gastrointestinal [GI] …
NMR study of a Lewisx pentasaccharide derivative: solution structure and interaction with cations
B Henry, H Desvaux, M Pristchepa, P Berthault… - Carbohydrate …, 1999 - Elsevier
The structure and conformation of the synthetic pentasaccharide Gal(β1-4){Fuc(α1-3)}GlcNAc(β1-3)Gal(β1-4)Glc-βOMe
of the Lewis X family has been determined by NMR …
of the Lewis X family has been determined by NMR …
[HTML][HTML] Laboratory abnormalities in children with novel coronavirus disease 2019
The novel coronavirus disease 2019 (COVID-19), a cause of respiratory and systemic illness,
continues to progress toward global pandemic. As of March 6, 2020, the World Health …
continues to progress toward global pandemic. As of March 6, 2020, the World Health …
Lactate dehydrogenase levels predict coronavirus disease 2019 (COVID-19) severity and mortality: A pooled analysis
BM Henry, G Aggarwal, J Wong, S Benoit… - The American journal of …, 2020 - Elsevier
… The enzyme is composed by two major subunits (ie, A and B), and is present in humans in
five separate isozymes (LDH-1 in cardiomyocytes, LDH-2 in reticuloendothelial system, LDH-…
five separate isozymes (LDH-1 in cardiomyocytes, LDH-2 in reticuloendothelial system, LDH-…
Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a meta-analysis
Background Coronavirus disease 2019 (COVID-19) is a novel infectious disease with lack
of established laboratory markers available to evaluate illness severity. In this study, we …
of established laboratory markers available to evaluate illness severity. In this study, we …