Genome variation and population structure among 1142 mosquitoes of the African malaria vector species Anopheles gambiae and Anopheles coluzzii
…, C Mbogo, P Bejon, V Robert, HD Mawejje… - Genome …, 2020 - genome.cshlp.org
Mosquito control remains a central pillar of efforts to reduce malaria burden in sub-Saharan
Africa. However, insecticide resistance is entrenched in malaria vector populations, and …
Africa. However, insecticide resistance is entrenched in malaria vector populations, and …
Insecticide resistance monitoring of field‐collected Anopheles gambiae sl. populations from Jinja, eastern Uganda, identifies high levels of pyrethroid resistance
HD Mawejje, CS Wilding, EJ Rippon… - Medical and …, 2013 - Wiley Online Library
Insecticide resistance in the malaria vector Anopheles gambiae sl. (Diptera: Culicidae)
threatens insecticide‐based control efforts, necessitating regular monitoring. We assessed …
threatens insecticide‐based control efforts, necessitating regular monitoring. We assessed …
Contemporary evolution of resistance at the major insecticide target site gene Ace‐1 by mutation and copy number variation in the malaria mosquito Anopheles …
…, AE Yawson, J Essandoh, HD Mawejje… - Molecular …, 2015 - Wiley Online Library
Functionally constrained genes are ideal insecticide targets because disruption is often fatal,
and resistance mutations are typically costly. Synaptic acetylcholinesterase ( AC hE) is an …
and resistance mutations are typically costly. Synaptic acetylcholinesterase ( AC hE) is an …
[HTML][HTML] Candidate-gene based GWAS identifies reproducible DNA markers for metabolic pyrethroid resistance from standing genetic variation in East African …
…, K Steen, EJ Rippon, JC Morgan, HD Mawejje… - Scientific reports, 2018 - nature.com
Metabolic resistance to pyrethroid insecticides is widespread in Anopheles mosquitoes and
is a major threat to malaria control. DNA markers would aid predictive monitoring of …
is a major threat to malaria control. DNA markers would aid predictive monitoring of …
[HTML][HTML] Insecticide resistance in areas under investigation by the International Centers of Excellence for Malaria Research: a challenge for malaria control and …
…, M Palomino, MJ Donnelly, HD Mawejje… - The American journal …, 2015 - ncbi.nlm.nih.gov
Scale-up of the main vector control interventions, residual insecticides sprayed on walls or
structures and/or impregnated in bed nets, together with prompt diagnosis and effective …
structures and/or impregnated in bed nets, together with prompt diagnosis and effective …
[HTML][HTML] Genome-wide transcriptional analyses in Anopheles mosquitoes reveal an unexpected association between salivary gland gene expression and insecticide …
Background To combat malaria transmission, the Ugandan government has embarked
upon an ambitious programme of indoor residual spraying (IRS) with a carbamate class …
upon an ambitious programme of indoor residual spraying (IRS) with a carbamate class …
[HTML][HTML] Contemporary gene flow between wild An. gambiae ss and An. arabiensis
D Weetman, K Steen, EJ Rippon, HD Mawejje… - Parasites & vectors, 2014 - Springer
Background In areas where the morphologically indistinguishable malaria mosquitoes
Anopheles gambiae Giles and An. arabiensis Patton are sympatric, hybrids are detected …
Anopheles gambiae Giles and An. arabiensis Patton are sympatric, hybrids are detected …
[HTML][HTML] Strain characterisation for measuring bioefficacy of ITNs treated with two active ingredients (Dual-AI ITNs): developing a robust protocol by building consensus
…, SR Irish, W Kisinza, N Lissenden, HD Mawejje… - Insects, 2022 - mdpi.com
Simple Summary New types of bed nets are being developed which contain a pyrethroid
plus a second chemical because of the development and increased frequency of mosquito …
plus a second chemical because of the development and increased frequency of mosquito …
[HTML][HTML] East Africa International Center of Excellence for Malaria Research: Summary of Key Research Findings
…, SL Nsobya, V Asua, HD Mawejje… - The American journal …, 2022 - ncbi.nlm.nih.gov
The Program for Resistance, Immunology, Surveillance, and Modeling of Malaria (PRISM)
has been conducting malaria research in Uganda since 2010 to improve the understanding of …
has been conducting malaria research in Uganda since 2010 to improve the understanding of …
[HTML][HTML] Mechanisms of transcriptional regulation in Anopheles gambiae revealed by allele specific expression
…, JH Brenas, A Miles, CS Clarkson, HD Mawejje… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Malaria control relies on insecticides targeting the mosquito vector, but this is increasingly
compromised by insecticide resistance, which can be achieved by elevated expression of …
compromised by insecticide resistance, which can be achieved by elevated expression of …