Adeno-associated viral (AAV) vectors have emerged as gene therapy and vaccine delivery
systems. Differential scanning fluorimetry or differential scanning calorimetry is commonly …

This population‐based study documented β‐blocker use in 59/569 cases with incident
fracture and 112/775 controls. OR for fracture associated with β‐blocker use was 0.68 (95%CI, …

In this population-based, observational study, we document the personal burden of fracture
and utilization of community and health services for women during the 12-month period …

Viroporins are small viral ion channels that play important roles in the viral infection cycle
and are proven antiviral drug targets. Matrix protein 2 from influenza A (AM2) is the best-…

In this population‐based study, seasonal periodicity was seen with reduced serum vitamin D,
increased serum PTH, and increased bone resorption in winter. This was associated with …

Under certain cellular conditions, functional proteins undergo misfolding, leading to a
transition into oligomers which precede the formation of amyloid fibrils. Misfolding proteins are …

To determine the age- and BMD-specific burden of fractures in the community and the cost-effectiveness
of targeted drug therapy, we studied a demographically well-categorized …

Background Recent data suggest that 3-hydroxy-3-methylglutaryl coenzyme A reductase
inhibitors (statins) decrease fracture risk and increase bone mineral density (BMD). Methods …

Lipid membranes have recently been implicated in protein misfolding and disease etiology,
including for α-synuclein and Parkinson’s disease. However, studying the intersection of …

Native mass spectrometry (MS) and charge detection-mass spectrometry (CD-MS) have
become versatile tools for characterizing a wide range of proteins and macromolecular …