Leishmaniasis is a neglected disease, for which current treatment presents numerous issues.
Leishmania amazonensis is the etiological agent of cutaneous and diffuse cutaneous …

Leishmania (Viannia) braziliensis induces American tegumentary leishmaniasis that ranges
in severity from the milder form, cutaneous (CL) to severe disseminated cutaneous …

Neutrophils play an important role in the outcome of leishmaniasis, contributing either to
exacerbating or controlling the progression of infection, a dual effect whose underlying …

Recombinant filamentous fd bacteriophages (rfd) expressing antigenic peptides were shown
to induce cell-mediated immune responses in the absence of added adjuvant, being a …

Zika virus (ZIKV) emerged as an important infectious disease agent in Brazil in 2016. Infection
usually leads to mild symptoms, but severe congenital neurological disorders and Guillain-…

… The OPB from L. amazonensis were first cloned and sequenced by de Matos Guedes et al.
(… identified in humans (de Matos Guedes et al. 2007; de Matos Guedes et al. 2008). The VHTS …

Subtilisin proteases, found in all organisms, are enzymes important in the post-translational
steps of protein processing. In Leishmania major and L. donovani, this enzyme has been …

Clinical and experimental studies have described eosinophil infiltration in Leishmania
amazonensis infection sites, positioning eosinophils strategically adjacent to the protozoan-…

The relative potency and quality of mouse B cell response to Toll-like receptors (TLRs)
signaling varies significantly depending on the B cell subset and on the TLR member being …

Zika virus (ZIKV) emerged as an important infectious disease agent in Brazil in 2016. Infection
usually leads to mild symptoms but severe congenital neurological disorders and Guillain-…