User profiles for Hernan A. Lorenzi
Hernán A. LorenziDirector TriLab Bioinformatics Group Verified email at nih.gov Cited by 6809 |
[HTML][HTML] Study of the impact of long-duration space missions at the International Space Station on the astronaut microbiome
Over the course of a mission to the International Space Station (ISS) crew members are
exposed to a number of stressors that can potentially alter the composition of their microbiomes …
exposed to a number of stressors that can potentially alter the composition of their microbiomes …
Hippocampal hypocellularity in the Ts65Dn mouse originates early in development
HA Lorenzi, RH Reeves - Brain research, 2006 - Elsevier
Ts65Dn, a well-characterized animal model for Down syndrome, has three copies of the
distal end of mouse chromosome 16 and therefore has segmental trisomy for orthologs for …
distal end of mouse chromosome 16 and therefore has segmental trisomy for orthologs for …
[HTML][HTML] Impact of intrapartum and postnatal antibiotics on the gut microbiome and emergence of antimicrobial resistance in infants
T Tapiainen, P Koivusaari, L Brinkac, HA Lorenzi… - Scientific reports, 2019 - nature.com
Altogether, 20–30% of women receive intrapartum antibiotic prophylaxis (IAP) to prevent
sepsis in infants and 2–5% of newborn infants receive antibiotics due to suspected sepsis. …
sepsis in infants and 2–5% of newborn infants receive antibiotics due to suspected sepsis. …
[HTML][HTML] Metagenomic exploration of viruses throughout the Indian Ocean
The characterization of global marine microbial taxonomic and functional diversity is a primary
goal of the Global Ocean Sampling Expedition. As part of this study, 19 water samples …
goal of the Global Ocean Sampling Expedition. As part of this study, 19 water samples …
[HTML][HTML] Identification of a novel protein complex essential for effector translocation across the parasitophorous vacuole membrane of Toxoplasma gondii
…, A Naor, S Rastogi, KR Buchholz, HA Lorenzi… - PLoS …, 2018 - journals.plos.org
Toxoplasma gondii is an obligate intracellular parasite that can infect virtually all nucleated
cells in warm-blooded animals. The ability of Toxoplasma tachyzoites to infect and …
cells in warm-blooded animals. The ability of Toxoplasma tachyzoites to infect and …
[HTML][HTML] New Assembly, Reannotation and Analysis of the Entamoeba histolytica Genome Reveal New Genomic Features and Protein Content Information
Background In order to maintain genome information accurately and relevantly, original
genome annotations need to be updated and evaluated regularly. Manual reannotation of …
genome annotations need to be updated and evaluated regularly. Manual reannotation of …
[HTML][HTML] The genome and transcriptome of the enteric parasite Entamoeba invadens, a model for encystation
GM Ehrenkaufer, GD Weedall, D Williams, HA Lorenzi… - Genome biology, 2013 - Springer
Background Several eukaryotic parasites form cysts that transmit infection. The process is
found in diverse organisms such as Toxoplasma, Giardia, and nematodes. In Entamoeba …
found in diverse organisms such as Toxoplasma, Giardia, and nematodes. In Entamoeba …
[HTML][HTML] Sequencing and analysis of globally obtained human respiratory syncytial virus A and B genomes
Background Human respiratory syncytial virus (RSV) is the leading cause of respiratory tract
infections in children globally, with nearly all children experiencing at least one infection by …
infections in children globally, with nearly all children experiencing at least one infection by …
[HTML][HTML] The challenge of maintaining a healthy microbiome during long-duration space missions
AA Voorhies, HA Lorenzi - Frontiers in Astronomy and Space …, 2016 - frontiersin.org
Astronauts will face a host of challenges on long-duration space missions like a human
expedition to Mars, including the difficulty of maintaining a balanced and healthy microbiome. …
expedition to Mars, including the difficulty of maintaining a balanced and healthy microbiome. …
Vertical transmission of gut microbiome and antimicrobial resistance genes in infants exposed to antibiotics at birth
Vertical transmission of maternal microbes is a major route for establishing the gut microbiome
in newborns. The impact of perinatal antibiotics on vertical transmission of microbes and …
in newborns. The impact of perinatal antibiotics on vertical transmission of microbes and …