User profiles for Hernan A. Lorenzi

Hernán A. Lorenzi

Director TriLab Bioinformatics Group
Verified email at nih.gov
Cited by 6809

[HTML][HTML] Study of the impact of long-duration space missions at the International Space Station on the astronaut microbiome

…, K Moncera, Y Zhang, E Zurek, HA Lorenzi - Scientific Reports, 2019 - nature.com
Over the course of a mission to the International Space Station (ISS) crew members are
exposed to a number of stressors that can potentially alter the composition of their microbiomes …

Hippocampal hypocellularity in the Ts65Dn mouse originates early in development

HA Lorenzi, RH Reeves - Brain research, 2006 - Elsevier
Ts65Dn, a well-characterized animal model for Down syndrome, has three copies of the
distal end of mouse chromosome 16 and therefore has segmental trisomy for orthologs for …

[HTML][HTML] Impact of intrapartum and postnatal antibiotics on the gut microbiome and emergence of antimicrobial resistance in infants

T Tapiainen, P Koivusaari, L Brinkac, HA Lorenzi… - Scientific reports, 2019 - nature.com
Altogether, 20–30% of women receive intrapartum antibiotic prophylaxis (IAP) to prevent
sepsis in infants and 2–5% of newborn infants receive antibiotics due to suspected sepsis. …

[HTML][HTML] Metagenomic exploration of viruses throughout the Indian Ocean

SJ Williamson, LZ Allen, HA Lorenzi, DW Fadrosh… - 2012 - journals.plos.org
The characterization of global marine microbial taxonomic and functional diversity is a primary
goal of the Global Ocean Sampling Expedition. As part of this study, 19 water samples …

[HTML][HTML] Identification of a novel protein complex essential for effector translocation across the parasitophorous vacuole membrane of Toxoplasma gondii

…, A Naor, S Rastogi, KR Buchholz, HA Lorenzi… - PLoS …, 2018 - journals.plos.org
Toxoplasma gondii is an obligate intracellular parasite that can infect virtually all nucleated
cells in warm-blooded animals. The ability of Toxoplasma tachyzoites to infect and …

[HTML][HTML] New Assembly, Reannotation and Analysis of the Entamoeba histolytica Genome Reveal New Genomic Features and Protein Content Information

HA Lorenzi, D Puiu, JR Miller, LM Brinkac… - PLoS neglected …, 2010 - journals.plos.org
Background In order to maintain genome information accurately and relevantly, original
genome annotations need to be updated and evaluated regularly. Manual reannotation of …

[HTML][HTML] The genome and transcriptome of the enteric parasite Entamoeba invadens, a model for encystation

GM Ehrenkaufer, GD Weedall, D Williams, HA Lorenzi… - Genome biology, 2013 - Springer
Background Several eukaryotic parasites form cysts that transmit infection. The process is
found in diverse organisms such as Toxoplasma, Giardia, and nematodes. In Entamoeba …

[HTML][HTML] Sequencing and analysis of globally obtained human respiratory syncytial virus A and B genomes

…, MI Nelson, J Bera, RA Halpin, CD Town, HA Lorenzi… - Plos one, 2015 - journals.plos.org
Background Human respiratory syncytial virus (RSV) is the leading cause of respiratory tract
infections in children globally, with nearly all children experiencing at least one infection by …

[HTML][HTML] The challenge of maintaining a healthy microbiome during long-duration space missions

AA Voorhies, HA Lorenzi - Frontiers in Astronomy and Space …, 2016 - frontiersin.org
Astronauts will face a host of challenges on long-duration space missions like a human
expedition to Mars, including the difficulty of maintaining a balanced and healthy microbiome. …

Vertical transmission of gut microbiome and antimicrobial resistance genes in infants exposed to antibiotics at birth

W Li, T Tapiainen, L Brinkac, HA Lorenzi… - The Journal of …, 2021 - academic.oup.com
Vertical transmission of maternal microbes is a major route for establishing the gut microbiome
in newborns. The impact of perinatal antibiotics on vertical transmission of microbes and …