Our current view of T cell differentiation and population dynamics is assembled from pieces
of data obtained from separate experimental systems and is thus patchy. We reassessed …

Background: Molecular typing is a valuable tool for gaining insight into spread of Mycobacterium
tuberculosis. Typing allows for clustering of cases whose isolates share an identical …

Background Since the roll-out of COVID-19 vaccines in late 2020 and throughout 2021,
European governments have relied on mathematical modelling to inform policy decisions about …

A seasonal rise in tuberculosis (TB) notifications has been confirmed in several studies. Here,
we examined one hypothesis for its cause: increased transmission of TB during wintertime …

Background. Scarlet fever, an infectious disease caused by Streptococcus pyogenes, largely
disappeared in developed countries during the twentieth century. In recent years, scarlet …

Immunodeficiency following autologous CD34 + -purified peripheral blood stem cell (PBSC)
transplantation could be related to T-cell depletion of the graft or impaired T-cell …

Objectives: IL-2 therapy increases memory and naive CD4 T cells in HIV-infected patients,
but its effect on thymopoiesis is unknown. To investigate this effect, we quantified T-cell …

Background While the burden of community‐acquired pneumonia and invasive pneumococcal
disease ( IPD ) is still considerable, there is little insight in the factors contributing to …

Background: BCG vaccine protects against the severe forms of tuberculosis (TB) in children.
Several low-prevalence countries are reviewing their policy, usually shifting from universal …

While tuberculosis (TB) represents a significant disease burden worldwide, low-incidence
countries strive to reach the WHO target of pre-elimination by 2035. Screening for TB in …