Persistent neural activity maintains information that connects past and future events. Models
of persistent activity often invoke reverberations within local cortical circuits, but long-range …

The neural substrates that the fruitfly Drosophila uses to sense smell, taste and light share
marked structural and functional similarities with ours, providing attractive models to dissect …

Behavior cannot be predicted from a "connectome" because the brain contains a chemical "map"
of neuromodulation superimposed upon its synaptic connectivity map. …

Optogenetics allows the manipulation of neural activity in freely moving animals with
millisecond precision, but its application in Drosophila melanogaster has been limited. Here we …

Short-term memories link events separated in time, such as past sensation and future
actions. Short-term memories are correlated with slow neural dynamics, including selective …

10.7554/eLife.11346.001 How brains are hardwired to produce aggressive behavior, and
how aggression circuits are related to those that mediate courtship, is not well understood. A …

An organism's behavioral decisions often depend upon the relative strength of appetitive and
aversive sensory stimuli, the relative sensitivity to which can be modified by internal states …

Optogenetics allows manipulations of genetically and spatially defined neuronal populations
with excellent temporal control. However, neurons are coupled with other neurons over …

The brain plans and executes volitional movements. The underlying patterns of neural
population activity have been explored in the context of movements of the eyes, limbs, tongue, …

Neurons in multiple brain regions fire trains of action potentials anticipating specific movements,
but this “preparatory activity” has not been systematically compared across behavioral …