User profiles for Hideo Otsuna

Hideo Otsuna

Data Scientist
Verified email at janelia.hhmi.org
Cited by 3657

A connectome and analysis of the adult Drosophila central brain

…, PH Li, L Lindsey, N Neubarth, DJ Olbris, H Otsuna… - elife, 2020 - elifesciences.org
The neural circuits responsible for animal behavior remain largely unknown. We summarize
new methods and present the circuitry of a large fraction of the brain of the fruit fly …

Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

GT Eisenhoffer, PD Loftus, M Yoshigi, H Otsuna… - Nature, 2012 - nature.com
For an epithelium to provide a protective barrier, it must maintain homeostatic cell numbers
by matching the number of dividing cells with the number of dying cells. Although …

Systematic analysis of the visual projection neurons of Drosophila melanogaster. I. Lobula‐specific pathways

H Otsuna, K Ito - Journal of Comparative Neurology, 2006 - Wiley Online Library
In insects, visual information is processed in the optic lobe and conveyed to the central brain.
Although neural circuits within the optic lobe have been studied extensively, relatively little …

A Connectome of the Adult Drosophila Central Brain

…, PH Li, L Lindsey, N Neubarth, DJ Olbris, H Otsuna… - BioRxiv, 2020 - biorxiv.org
The neural circuits responsible for behavior remain largely unknown. Previous efforts have
reconstructed the complete circuits of small animals, with hundreds of neurons, and selected …

Processing of Horizontal Optic Flow in Three Visual Interneurons of the Drosophila Brain

…, F Forstner, SV Raghu, H Otsuna… - Journal of …, 2010 - journals.physiology.org
Motion vision is essential for navigating through the environment. Due to its genetic amenability,
the fruit fly Drosophila has been serving for a lengthy period as a model organism for …

A complex choreography of cell movements shapes the vertebrate eye

KM Kwan, H Otsuna, H Kidokoro, KR Carney… - …, 2012 - journals.biologists.com
Optic cup morphogenesis (OCM) generates the basic structure of the vertebrate eye.
Although it is commonly depicted as a series of epithelial sheet folding events, this does not …

Synaptic activity and activity-dependent competition regulates axon arbor maturation, growth arrest, and territory in the retinotectal projection

NB Fredj, S Hammond, H Otsuna… - Journal of …, 2010 - Soc Neuroscience
In the retinotectal projection, synapses guide retinal ganglion cell (RGC) axon arbor growth
by promoting branch formation and by selectively stabilizing branches. To ask whether …

FluoRender: an application of 2D image space methods for 3D and 4D confocal microscopy data visualization in neurobiology research

Y Wan, H Otsuna, CB Chien… - 2012 IEEE Pacific …, 2012 - ieeexplore.ieee.org
2D image space methods are processing methods applied after the volumetric data are
projected and rendered into the 2D image space, such as 2D filtering, tone mapping and …

Topological and modality-specific representation of somatosensory information in the fly brain

…, T Yano, TK Yokoyama, C Murtin, H Otsuna… - Science, 2017 - science.org
Insects and mammals share similarities of neural organization underlying the perception of
odors, taste, vision, sound, and gravity. We observed that insect somatosensation also …

An interactive visualization tool for multi-channel confocal microscopy data in neurobiology research

Y Wan, H Otsuna, CB Chien… - IEEE transactions on …, 2009 - ieeexplore.ieee.org
Confocal microscopy is widely used in neurobiology for studying the three-dimensional structure
of the nervous system. Confocal image data are often multi-channel, with each channel …