Viral diseases are one of the leading causes of morbidity and mortality in the world. Virus-specific
vaccines and antiviral drugs are the most powerful tools to combat viral diseases. …

According to the WHO, there is an urgent need for better control of viral diseases. Re-positioning
existing safe-in-human antiviral agents from one viral disease to another could play a …

As of June 2020, the number of people infected with severe acute respiratory coronavirus 2 (SARS-CoV-2)
continues to skyrocket, with more than 6.7 million cases worldwide. Both the …

Combination therapies have become a standard for the treatment for HIV and hepatitis C
virus (HCV) infections. They are advantageous over monotherapies due to better efficacy, …

Background: There is an urgent need for new antivirals with powerful therapeutic potential
and tolerable side effects. Methods: Here, we tested the antiviral properties of interferons (IFNs…

Autoimmune diseases are characterized by chronic inflammatory reactions localized to an
organ or organ-system. They are caused by loss of immunologic tolerance toward self-…

SARS-CoV-2 and its vaccine/immune-escaping variants continue to pose a serious threat to
public health due to a paucity of effective, rapidly deployable, and widely available …

Macrolide-resistant strains of Mycoplasma genitalium are an increasing problem throughout
the world, and the implementation of a rapid and sensitive assay for mutation detection to …

Background: The evidence that pan-Bcl-2 or Bcl-xL-specific inhibitors prematurely kill virus-infected
or RNA/DNA-transfected cells provides rationale for investigating these apoptotic …

Background: Every year, millions of people are hospitalized and thousands die from influenza
A virus (FLUAV) infection. Most cases of hospitalizations and death occur among the …