User profiles for Hillel Ori

Hillel Ori

postdoc, Harvard University
Verified email at g.harvard.edu
Cited by 80

Dynamic clamp constructed phase diagram for the Hodgkin and Huxley model of excitability

H Ori, H Hazan, E Marder… - Proceedings of the …, 2020 - National Acad Sciences
Excitability—a threshold-governed transient in transmembrane voltage—is a fundamental
physiological process that controls the function of the heart, endocrine, muscles, and neuronal …

[HTML][HTML] Observation of topological action potentials in engineered tissues

H Ori, M Duque, R Frank Hayward, C Scheibner… - Nature Physics, 2023 - nature.com
The interface between two tissues can have very different bioelectrical properties compared
to either tissue on its own. Here we show that an interface between non-excitable tissues …

Cellular function given parametric variation in the Hodgkin and Huxley model of excitability

H Ori, E Marder, S Marom - Proceedings of the National …, 2018 - National Acad Sciences
How is reliable physiological function maintained in cells despite considerable variability in
the values of key parameters of multiple interacting processes that govern that function? Here…

[PDF][PDF] Electric-induced reversal of morphogenesis in Hydra

E Braun, H Ori - Biophysical journal, 2019 - cell.com
Morphogenesis involves the dynamic interplay of biochemical, mechanical, and electrical
processes. Here, we ask to what extent can the course of morphogenesis be modulated and …

Spiking at the edge: Excitability at interfaces in reaction–diffusion systems

C Scheibner, H Ori, AE Cohen… - Proceedings of the …, 2024 - National Acad Sciences
Excitable media, ranging from bioelectric tissues and chemical oscillators to forest fires and
competing populations, are nonlinear, spatially extended systems capable of spiking. Most …

Spiking at the edge

C Scheibner, H Ori, AE Cohen, V Vitelli - arXiv preprint arXiv:2304.06940, 2023 - arxiv.org
Excitable media, ranging from bioelectric tissues and chemical oscillators to forest fires and
competing populations, are nonlinear, spatially extended systems capable of spiking. Most …

Dynamic clamp constructed phase diagram of the Hodgkin-Huxley action potential model

H Ori, H Hazan, E Marder, S Marom - bioRxiv, 2019 - biorxiv.org
Excitability – a threshold governed transient in transmembrane voltage – is a fundamental
physiological process that controls the function of the heart, endocrine, muscles and neuronal …

Cellular function given parametric variation: excitability in the Hodgkin-Huxley model

H Ori, E Marder, S Marom - arXiv preprint arXiv:1805.07528, 2018 - arxiv.org
How is reliable physiological function maintained in cells despite considerable variability in
the values of key parameters of multiple interacting processes that govern that function? …

[PDF][PDF] Dynamic clamp constructed phase diagram of the Hodgkin-Huxley action potential

H Ori, H Hazan, E Marderb, S Maroma - Neuroscience, 2001 - researchgate.net
The canonical Hodgkin-Huxley model of excitability (Hodgkin and Huxley, 1952) consists of
four dynamical variables (membrane voltage and three protein state variables) and more …

Clinical and functional efficacy of elexacaftor/tezacaftor/ivacaftor in people with cystic fibrosis carrying the N1303K mutation

…, I Sarouk, O Breuer, J Reiter, A Gileles-Hillel… - Journal of Cystic …, 2023 - Elsevier
Background Elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) significantly improves health
outcomes in people with cystic fibrosis (pwCF) carrying one or two F508del mutations. …