We demonstrate a new strategy for the construction of supramolecular hemoprotein
assemblies. A synthetic heme was selectively introduced onto the surface Cys residue of the …

Virus-like particles (VLPs) have proven to be versatile platforms for chemical and genetic
functionalization for a variety of purposes in biomedicine, catalysis, and materials science. We …

Qβ virus-like particles encapsulating multiple copies of fluorescent proteins were generated
in high yields using a modular system enhanced by specific engineered RNA–protein …

Carbon monoxide (CO) is a gaseous molecule known as the silent killer. It is widely believed
that an increase in blood carboxyhemoglobin (CO-Hb) is the best biomarker to define CO …

The physiological roles of endogenous carbon monoxide (CO) have not been fully understood
because of the difficulty in preparing a loss-of-function phenotype of this molecule. Here, …

Supramolecular protein polymers: When a heme moiety was introduced to the surface of an
apo‐cytochrome b 562 (H63C) mutant, supramolecular polymers formed through …

Circadian rhythms are regulated by transcription-translation feedback loops (TTFL) of clock
genes. Previous studies have demonstrated that core transcriptional factors, NPAS2 and …

The 1:1 inclusion complex of 5,10,15,20-tetrakis(4-sulfonatophenyl)porphinato iron(II) (Fe II
TPPS) and an O-methylated β-cyclodextrin dimer having a pyridine linker (1) binds dioxygen …

Carbon monoxide (CO) is produced in mammalian cells during heme metabolism and serves
as an important signaling messenger. Here we report the bioactive properties of selective …

Simultaneous poisoning by carbon monoxide (CO) and hydrogen cyanide is the major cause
of mortality in fire gas accidents. Here, we report on the invention of an injectable antidote …