We have identified a Drosophila homolog of vertebrate classic cadherins. A monoclonal
antibody to Drosophila α-catenin (Dα-catenin) copurifies a 150-kDa glycoprotein (gp150) along …

DuringDrosophilagastrulation, morphogenesis occurs as a series of cell shape changes and
cell movements which probably involve adhesive interactions between cells. In the present …

Background The duplication of genes can occur through various mechanisms and is thought
to make a major contribution to the evolutionary diversification of organisms. There is …

Adhesion between cells is essential to the evolution of multicellularity. Indeed, morphogenesis
in animals requires firm but flexible intercellular adhesions that are mediated by …

Invagination of the epithelial cell sheet of the prospective mesoderm in Drosophila gastrulation
is a well-studied, relatively simple morphogenetic event that results from dynamic cell …

Dynamic epithelial reorganization is essential for morphogenesis of various organs. In Drosophila
embryos, for example the Malpighian tubule is generated by cellular rearrangement of …

In early embryogenesis of spiders, the cumulus is characteristically observed as a cellular
thickening that arises from the center of the germ disc and moves centrifugally. This cumulus …

Coordination of cell motility and adhesion is essential for concerted movement of tissues
during animal morphogenesis. The Drosophila tracheal network is formed by branching, …

Background Although autologous nerve grafting is the gold standard treatment of peripheral
nerve injuries, several alternative methods have been developed, including nerve conduits …

The mechanism by which Decapentaplegic (Dpp) and its antagonist Short gastrulation (Sog)
specify the dorsoventral pattern in Drosophilaembryos has been proposed to have a …