[HTML][HTML] Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy
…, J Winkelmann, T Miyagawa, H Toyoda… - Nature …, 2023 - nature.com
Narcolepsy type 1 (NT1) is caused by a loss of hypocretin/orexin transmission. Risk factors
include pandemic 2009 H1N1 influenza A infection and immunization with Pandemrix®. Here…
include pandemic 2009 H1N1 influenza A infection and immunization with Pandemrix®. Here…
Anti-Tribbles homolog 2 autoantibodies in Japanese patients with narcolepsy
H Toyoda, S Tanaka, T Miyagawa, Y Honda… - Sleep, 2010 - academic.oup.com
Study Objectives: Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness
and cataplexy. The association with human leukocyte antigen (HLA)-DQB1*0602 and T-…
and cataplexy. The association with human leukocyte antigen (HLA)-DQB1*0602 and T-…
A polymorphism in CCR1/CCR3 is associated with narcolepsy
H Toyoda, T Miyagawa, A Koike, T Kanbayashi… - Brain, behavior, and …, 2015 - Elsevier
Etiology of narcolepsy–cataplexy involves multiple genetic and environmental factors. While
the human leukocyte antigen (HLA)-DRB1*15:01-DQB1*06:02 haplotype is strongly …
the human leukocyte antigen (HLA)-DRB1*15:01-DQB1*06:02 haplotype is strongly …
[HTML][HTML] Sensitivity to gene dosage and gene expression affects genes with copy number variants observed among neuropsychiatric diseases
Background Copy number variants (CNVs) have been reported to be associated with diseases,
traits, and evolution. However, it is hard to determine which gene should have priority as …
traits, and evolution. However, it is hard to determine which gene should have priority as …
New susceptibility variants to narcolepsy identified in HLA class II region
T Miyagawa, H Toyoda, A Hirataka… - Human molecular …, 2015 - academic.oup.com
Narcolepsy, a sleep disorder characterized by excessive daytime sleepiness, cataplexy and
rapid eye movement sleep abnormalities, is tightly associated with human leukocyte antigen …
rapid eye movement sleep abnormalities, is tightly associated with human leukocyte antigen …
Cooling history of some Antarctic ureilites
…, H Takeda, H Toyoda - Journal of Geophysical …, 1985 - Wiley Online Library
To obtain some constraints on the cooling histories of ureilites, we have studied the
chemical zoning of olivines and the compositional variations of pyroxenes in the PCA82506, …
chemical zoning of olivines and the compositional variations of pyroxenes in the PCA82506, …
Increased plasma IL-6, IL-8, TNF-alpha, and G-CSF in Japanese narcolepsy
S Tanaka, M Honda, H Toyoda, T Kodama - Human immunology, 2014 - Elsevier
Narcolepsy is a chronic hypersomnia involving excessive daytime sleepiness and cataplexy.
Some susceptibility genes and environmental factors suggest that post-infectious …
Some susceptibility genes and environmental factors suggest that post-infectious …
[HTML][HTML] Genome-wide association study of HLA-DQB1* 06: 02 negative essential hypersomnia
SS Khor, T Miyagawa, H Toyoda, M Yamasaki… - PeerJ, 2013 - peerj.com
Essential hypersomnia (EHS), a sleep disorder characterized by excessive daytime sleepiness,
can be divided into two broad classes based on the presence or absence of the HLA-…
can be divided into two broad classes based on the presence or absence of the HLA-…
[HTML][HTML] Evaluation of polygenic risks for narcolepsy and essential hypersomnia
M Yamasaki, T Miyagawa, H Toyoda, SS Khor… - Journal of human …, 2016 - nature.com
In humans, narcolepsy is a sleep disorder that is characterized by sleepiness, cataplexy and
rapid eye movement (REM) sleep abnormalities. Essential hypersomnia (EHS) is another …
rapid eye movement (REM) sleep abnormalities. Essential hypersomnia (EHS) is another …
[HTML][HTML] An association analysis of HLA-DQB1 with narcolepsy without cataplexy and idiopathic hypersomnia with/without long sleep time in a Japanese population
T Miyagawa, H Toyoda, T Kanbayashi… - Human Genome …, 2015 - nature.com
Narcolepsy without cataplexy (NA w/o CA)(narcolepsy type 2) is a lifelong disorder characterized
by excessive daytime sleepiness and rapid eye movement (REM) sleep abnormalities, …
by excessive daytime sleepiness and rapid eye movement (REM) sleep abnormalities, …