Objective— The delivery of autologous progenitor cells into ischemic tissue of patients is
emerging as a novel therapeutic option. Here, we report the potential impact of cultured …

Cardiac hypertrophy is a major cause of morbidity and mortality worldwide. The hypertrophic
process is mediated, in part, by small G proteins of the Rho family. We hypothesized that …

Adult stem cells hold great promise for use in tissue repair and regeneration, and there has
been continuing interest in both the biology and potential therapeutic applications of adult …

Antibodies against the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein
prevent SARS-CoV-2 infection. However, the effects of antibodies against other spike protein …

Elimination of senescent cells (senolysis) was recently reported to improve normal and
pathological changes associated with aging in mice 1 , 2 . However, most senolytic agents inhibit …

Osteoprotegerin (OPG) is a soluble secreted protein and a decoy receptor, which inhibits a
receptor activator of nuclear factor κB (NF-κB) ligand (RANKL)/the receptor activator of NF-κB …

Background To investigate the effect of angiotensin (Ang) II type 1 receptor (AT 1 ) blocker on
vascular remodeling and explore the possibility of the involvement of Ang II type 2 receptor …

Type 2 diabetes is associated with a two to fourfold increased risk of both coronary heart
disease and stroke. Dysfunction of endothelial cells (EC) is known to promote abnormal …

Recent clinical studies suggest that several antihypertensive drugs, especially angiotensin‐converting
enzyme inhibitors, reduced bone fractures. To clarify the relationship between …

Cardiac hypertrophy is an adaptive response to increases in blood pressure. Recent studies
indicate that the hypertrophic process is associated with increases in intracellular oxidative …