Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP)

H Hashimoto, N Shintani, K Tanaka… - Proceedings of the …, 2001 - National Acad Sciences
Pituitary adenylate cyclase-activating polypeptide (PACAP) has been conserved remarkably
during evolution and is widely expressed in the mammalian brain. In Drosophila, mutation …

Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery

…, O Wurtz, A Fournier, BKC Chow, H Hashimoto… - Pharmacological …, 2009 - ASPET
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 38-amino acid C-terminally
α-amidated peptide that was first isolated 20 years ago from an ovine hypothalamic extract …

[HTML][HTML] Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes

…, K Takuma, R Hashimoto, H Hashimoto… - Nature …, 2020 - nature.com
Pogo transposable element derived with ZNF domain (POGZ) has been identified as one of
the most recurrently de novo mutated genes in patients with neurodevelopmental disorders (…

[HTML][HTML] Anomalous protein diffusion in living cells as seen by fluorescence correlation spectroscopy

M Weiss, H Hashimoto, T Nilsson - Biophysical journal, 2003 - cell.com
We investigate the challenges and limitations that are encountered when studying membrane
protein dynamics in vivo by means of fluorescence correlation spectroscopy (FCS). Based …

Distribution of the mRNA for a pituitary adenylate cyclase‐activating polypeptide receptor in the rat brain: an in situ hybridization study

H Hashimoto, H Nogi, K Mori, H Ohishi… - Journal of …, 1996 - Wiley Online Library
The distribution of the mRNA for a pituitary adenylate cyclase‐activating polypeptide (PACAP)
receptor (PACAP‐R) was examined in the rat brain, and also in the hypophysis and pineal …

Molecular cloning and tissue distribution of a receptor for pituitary adenylate cyclase-activating polypeptide

H Hashimoto, T Ishihara, R Shigemoto, K Mori… - Neuron, 1993 - cell.com
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a polypeptide hormone related
to vasoactive intestinal polypeptide (VIP). Rat PACAP receptor cDNA was isolated from a …

Molecular basis of astrocyte diversity and morphology across the CNS in health and disease

F Endo, A Kasai, JS Soto, X Yu, Z Qu, H Hashimoto… - Science, 2022 - science.org
Astrocytes, a type of glia, are abundant and morphologically complex cells. Here, we report
astrocyte molecular profiles, diversity, and morphology across the mouse central nervous …

Apelin is a novel angiogenic factor in retinal endothelial cells

…, N Shintani, M Oda, M Kakuda, H Hashimoto… - Biochemical and …, 2004 - Elsevier
There has been much focus recently on the possible functions of apelin, an endogenous
ligand for the orphan G-protein-coupled receptor APJ, in cardiovascular and central nervous …

Pituitary adenylate cyclase-activating polypeptide (PACAP) decreases ischemic neuronal cell death in association with IL-6

…, K Hodoyama, S Yofu, H Hashimoto… - Proceedings of the …, 2006 - National Acad Sciences
Pituitary adenylate cyclase-activating polypeptide (PACAP) has been reported to decrease
ischemic neuronal damage and increase IL-6 secretion in rats. However, the mechanisms …

Pituitary adenylate cyclase-activating polypeptide plays a key role in nitroglycerol-induced trigeminovascular activation in mice

…, J Tajti, J Szolcsanyi, E Pinter, H Hashimoto… - Neurobiology of …, 2012 - Elsevier
Pituitary adenylate cyclase-activating polypeptide (PACAP) and its receptors (PAC1, VPAC)
are present in sensory neurons and vascular smooth muscle. PACAP infusion was found to …