Induced pluripotent stem cell-derived neural stem cells (iNSCs) have significant potential as
an autologous, multifunctional cell therapy for stroke, which is the primary cause of long …

Introduction Neural stem cells (NSCs) have demonstrated multimodal therapeutic function
for stroke, which is the leading cause of long‐term disability and the second leading cause of …

Traumatic brain injury (TBI) is a major contributor of long-term disability and a leading cause
of death worldwide. A series of secondary injury cascades can contribute to cell death, …

Stroke is a major cause of death and long-term disability affecting seven million adults in the
United States each year. Recently, it has been demonstrated that neurological diseases, …

Background Efforts to develop stroke treatments have met with limited success despite an
intense need to produce novel treatments. The failed translation of many of these therapies in …

Induced pluripotent stem cell-derived neural stem cells (iNSCs) are a multimodal stroke
therapeutic that possess neuroprotective, regenerative, and cell replacement capabilities post-…

Traumatic brain injury (TBI) is a leading cause of death and disability in the United States,
with children who sustain a TBI having a greater risk of developing long-lasting cognitive, …

A number of pre-clinical rodent models have been developed in an effort to recapitulate injury
mechanisms and identify potential therapeutics for traumatic brain injury (TBI), which is a …

Traumatic brain injury (TBI) is a leading cause of death and disability in children. Pediatric
TBI patients often suffer from crippling cognitive, emotional, and motor function deficits that …

The acute stroke phase is a critical time frame used to evaluate stroke severity, therapeutic
options, and prognosis while also serving as a major tool for the development of diagnostics. …