Motivation: Most approaches in predicting protein function from protein–protein interaction
data utilize the observation that a protein often share functions with proteins that interacts with …

Motivation: Protein complexes are important for understanding principles of cellular organization
and function. High-throughput experimental techniques have produced a large amount …

Drug synergy allows a therapeutic effect to be achieved with lower doses of component
drugs. Drug synergy can result when drugs target the products of genes that act in parallel …

Protein complexes are fundamental for understanding principles of cellular organizations.
As the sizes of protein–protein interaction (PPI) networks are increasing, accurate and fast …

An increasing number of genes have been experimentally confirmed in recent years as
causative genes to various human diseases. The newly available knowledge can be exploited …

In higher eukaryotes, messenger RNAs (mRNAs) are exported from the nucleus to the
cytoplasm via factors deposited near the 5′ end of the transcript during splicing. The signal …

Threatened preterm labor (TPTL) is defined as persistent premature uterine contractions
between 20 and 37 weeks of gestation and is the most common condition that requires …

Motivation: With the increasing availability of diverse biological information, protein function
prediction approaches have converged towards integration of heterogeneous data. Many …

Protein interactions are crucial components of all cellular processes. An in-depth knowledge
of the full complement of protein interactions in a cell, therefore, provides insight into the …

Background Protein-protein interaction has been used to complement traditional sequence
homology to elucidate protein function. Most existing approaches only make use of direct …